Optimising bariatric surgery - By-Band-Sleeve study

The By-Band Sleeve study aims to identify the most effective bariatric (obesity treatment) surgery for patients’ health and cost to the NHS.

Treating obesity through surgery

Levels of obesity have tripled in the last 30 years with over 60 percent of adults in England overweight or obese, and more than 2.7 million people suffering from obesity-related type 2 diabetes.

Bariatric surgery is used to treat obesity in some cases and  involves modifying the stomach and digestive tract to restrict the size or working of the stomach, limiting the amount individuals can, or want to eat. 

Finding the best approach

Those taking part in By-Band-Sleeve will have an equal chance of being assigned any of the three kinds of bariatric surgery currently used in the NHS; gastric band, a gastric bypass, or a gastric sleeve.

James Byrne, consultant surgeon at University Hospital Southampton, is delivering the By-Band-Sleeve study at Southampton, discussing participation with patients referred to us for bariatric surgery.

What's involved

bybandsleevev3resizeYou can find in-depth information about participation on the By-Band-Sleeve website, here. Adults who are referred for bariatric surgery at Southampton can take part in the study. Patients are given some information to read about the study and the chance to discuss it with the health professionals on the team.

Those who agree to take part will have an equal chance of being assigned a gastric band, a gastric bypass, or a gastric sleeve. This allows the three types of operations to be compared in a balanced way.

Participants will be told which operation they have been assigned to several weeks before their actual operation date. It is planned that 1341 patients will take part in the study in total.

After surgery

After surgery, participants will be followed up carefully, including regular weight checks. They will be asked to complete questionnaires about their quality of life and use of healthcare. Some participants will also be interviewed about their experience.

Researchers will also ask participants to provide two blood samples for future research into obesity, in addition to the samples people would give as part of their normal care. All participants will be followed up by the study team for three years.

Southampton's commitment to better bariatric surgery

It is the latest study in James’ research, conducted through the multidisciplinary bariatric surgical research group he created in Southampton, involving patients, public health, health economic and diabetes and endocrinology experts to drive better bariatric surgery.