Research reveals few childrens' multivitamin products supply recommended vitamin D dose

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Few multivitamin products for children supply the recommended dose of 400 IU a day of vitamin D, suggest the results of a survey of 91 different products, published online in the Archives of Disease in Childhood.

Researchers at the University of Southampton and University of Oxford have revealed supplements containing only vitamin D or labelled specifically ‘for healthy bones’ typically had a higher vitamin D content, although some products ‘for bones’ contained very low levels of the vitamin.

"There is a wide range of both multivitamins and vitamin D supplements available for children in the UK, yet many of these do not provide the recommended 400 IU/day,” said Dr Rebecca Moon, who led the research at the Medical Research Council Lifecourse Epidemiology Unit (MRC LEU), University of Southampton.

"To obtain this, children would either have to take over the recommended dose, which may increase the risk of toxicity from the other components, or they would have to take a combination of vitamin D and multivitamins, which is more expensive."

Vitamin D advice

Low levels of vitamin D are common in children in the UK, particularly during the winter. Vitamin D deficiency can lead to rickets and abnormally low levels of calcium in the blood (hypocalcaemia)--conditions that can be prevented by taking vitamin D supplements.

In 2016, Public Health England recommended a daily dose of 400 IU all year round for all 1-4 year olds, and during the autumn and winter months for adults and children over the age of 4.

The Healthy Start scheme, a public health initiative for low income families in England, provides free multivitamins. But these products contain only 300 IU per day of vitamin D, prompting the researchers to see if other children’s multivitamins sold in the UK might contain less than the recommended amount. 

Comparing UK multivitamins

In September 2018, they searched the websites of nine UK supermarkets and high street health product retailers, looking for multivitamins aimed at children under the age of 12.

A product was considered a multivitamin if the packaging or manufacturer’s website included the word ‘multivitamin’ or a version of this, or if more than one vitamin was named. They also looked at products labelled as a vitamin D supplement, or which suggested they could help with ‘healthy bones’. If a dose range was advised, they recorded the highest amount, to quantify the daily amount of vitamin D provided.

The researchers found 67 multivitamins, made by 24 different manufacturers, and 24 vitamin D/healthy bones products aimed at children under the age of 12. The daily vitamin D dose in the multivitamins surveyed ranged from 0 to 800 IU.

Only one multivitamin was suitable for use from birth, supplying 200 IU/day of vitamin D, while for children over 6 months, only between a quarter and a third (25-36 per cent) of the available products supplied at least 400 IU/day.

Some of the products giving a dose range would only supply the recommended vitamin D level at the highest dose. The vitamin D/healthy bones products supplied between 50 and 1000 IU of vitamin D a day.  Six were suitable for use from birth, five of which contained 340-400 IU of vitamin D.

The vitamin D content of these types of supplement was typically higher than that of multivitamins: nearly two thirds (57-67 per cent) contained at least 400 IU/day. But one product labelled as ‘for bones and relaxation’ contained only 50 IU/day of vitamin D.

The researchers point out that their survey was limited to supplements sold by UK retailers, and many other supplements are available from online retailers, including imported products and fortified food products. But because multivitamins are classed as food products, under European Union regulations, the permissible vitamin D content can range from 20 per cent below, to 50 per cent above, the amount stated on the label, they say.

Check the label

”Work from our unit and elsewhere has demonstrated the importance of vitamin D in early life for bone and muscle health,” added Professor Nicholas Harvey, Professor of Rheumatology and Clinical Epidemiology at the MRC LEU, University of Southampton, who oversaw the project.

“Our findings inform the practicalities of ensuring that vitamin D intake is adequate in young children, and that it is important for parents and caregivers to check that the multivitamins they buy for children contain the recommended 400 IU vitamin D per day.”

Posted on Friday 1 March 2019