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RLP Guidance Notes Cohort 5 Final

Description: University Hospital Southampton Research Leaders Programme (RLP) Award Scheme Application Guidance Notes for Cohort 5 – April 2025 Please complete the application form and submit via MS forms https://forms.office.com/e/cE834Azafh by no later than 5.00pm on Friday 25th October 2024 (This includes emailing completed annexes A and B to RLP@uhs.nhs.uk) Applicants will be notified of the outcome by Friday 3rd January 2025. Introduction University Hospital Southampton Research & Development (R&D) secured a significant investment from University Hospital Southampton Trust Board in 2021 to establish a Research Leaders Programme (RLP), overseen and managed by the Southampton Academy of Research. This programme aims to identify staff of all clinical disciplines with research leadership potential, and provide them with time, training, and personal development to enable progression towards their agreed research career pathway. The purpose of the programme is to enable substantively employed UHS health care professionals to build a portfolio of research activity that will attract funding and facilitate research to become a significant and sustainable component of the award holder’s job plan within 3 years. The Awards are offered competitively. We are now seeking applications for the fifth cohort only. Individuals must be in the position and have the support of their manager to start week commencing Monday 7th April 2025. Types of awards The RLP comprises 2 different types of awards (with an option for these to be combined if explicitly agreed by discussion, ahead of application, with the RLP team) (see Figure 1): 1. Group A - Research Delivery Focused/Growing Principal Investigators (PI) 1 To build capacity to enable delivery of clinical research by providing protected time to undertake PI- related activities on externally funded NIHR CRN portfolio research studies, supported by a research team funded by external study income. Goal: To establish/significantly expand a portfolio of externally funded research studies, commercial and non-commercial. 2. Group B - Clinical Academic Focused/Growing Chief investigators (CI) To support healthcare professionals with significant potential to become independent researchers and fulfil the role of Chief Investigator2 by generating income through personal fellowships and/or leadership of grant applications. Goal: To secure external funding and lead a programme of externally funded research, in the context of a clinical academic position. OR: A combination of Group A and B (Mixed), explicitly agreed, with outcomes reflecting the blend. An application to this pathway MUST be discussed ahead of application with the RLP team. 1 Principal investigator: An individual responsible for the conduct of the research at a research site. There should be one PI for each research site. In the case of a single-site study, the chief investigator and the PI will normally be the same person. 2 Chief Investigator: the overall lead researcher for a research project and the lead applicant on the grant application in addition to their responsibilities if they are members of a research team, chief investigators are responsible for the overall conduct of a research project. They are responsible for intellectual leadership of the research project and for the overall management of the research (some funders refer to this as the PI 1 Updated on 7/8/24 Successful applicants will commit to a programme of activity utilising RLP funded protected time, with the goal of recovering investment through writing their time into grant applications and/or securing commercial income. They will, in turn, be supported to develop/augment a research delivery team through the external funding generated by the research they pursue. Participants will be selected through a competitive application process, with competitions spaced annually. The Award Scheme Each award will comprise several different elements – some are core (such as backfill, mentorship and leadership development) and others dependent on an individual’s learning, development, and support needs (e.g., fees for short courses, methodological support, coaching, explicit connections with UHS/UoS infrastructure). Two types of costs will be met: • Funds to cover the cost of salary backfill • Funds to support access to learning and development These are as follows: Type of support Funded protected time (core) Type of RLP fellow Both i.e. Group A and Group B Notes Minimum commitment expected of the award holder is 20% WTE. • For Medical Consultants, the protected time offered is 2PAs. Overall consultant PAs in job plan including RLP PAs must not exceed 12 PAs. Funding allocation Based on basic salary cost (Including employment costs) of individual. • For other HCP a higher WTE of up to 40% WTE will be considered. Even if the applicant works part time, they must be released for 1 full day per week. This will not be a pro rata arrangement. Please Note: If you choose to have protected time for less than the full 36 Months, you must still agree to attend the LaunchPad2Leadership Programme (L2L) for the full 3-year duration. Launchpad Both 2 Leadership Programme (core) Affiliated to, and supported by, the Trust Leadership Programmes. The L2L will run one half day per quarter, with a facilitator supporting shared learning amongst those enrolled on the scheme. Attendance at L2L is mandatory. No individual allocation. Costs of L2L met by programme budget. Attendance at SoAR Autumn/Spring Schools is also anticipated. 2 Updated on 7/8/24 The L2L team will signpost towards available programmes and resources (not funded as a component of the programme) bespoke to a training needs analysis for each person: e.g., AMS/NIHR Leadership Academy, UKRI Future Leadership, Florence Nightingale Foundation, Clinical Research Network (CRN) and local and national NHS Clinical Leadership Programmes. These can be undertaken in RLP time, personal time or SPA as agreed and recorded in the learning objectives of the award holder. Where required, these additional activities can be funded through either the RLP training budget (see below) or the individual’s existing study budget where applicable. Type of support Fees to support training needs in specific areas not already available free of charge through SoAR, UHS or UoS Type of RLP fellow Both see notes Notes Research Delivery (Group A) PG Cert, PGDip, or MRes that meet requirements of NIHR AoMRC Credentialing framework Funding allocation Applicants are expected to apply for NHS staff bursaries offered to support these activities where these exist. Should these not be available or the applicant be unsuccessful, funding support from RLP will be reviewed by the RLP team, based on the individuals needs assessment. Methodological Support Clinical Academic Clinical Academic (Group B) Accessing short courses to extend skills and knowledge necessary to develop high quality grant/fellowship applications. This may also extend to conferences where research work is being presented, following prior discussion with the RLP team. Any proposed activity should have been agreed in advance in the individual training needs/scoping review with the RLP team and Research Advisor (RA) – see below. Clinical Academic pathway: The RLP team will facilitate access to methodology and PPIE support from existing infrastructure where this is needed to support grant and fellowship applications. Funds to secure time from individuals with specific methodological expertise overcoming a specific barrier to grant/fellowship application success may be available on a case-by-case basis, following prior discussion with the RLP team. For example: complex statistics, health economics, trial design, qualitative methods. Each RLP award holder can apply for up to £1,000 per annum. (max 3 yrs.) This will be allocated on a first come, first served basis via our RLP request for training and development funding form. Via NIHR Research Support Service (RSS SC)/to be individually determined 3 Updated on 7/8/24 Coaching Both Should it be deemed by the RLP team that an Up to £1000 individual is facing a specific challenge for which executive coach would be appropriate, the individual may be offered the opportunity to work with a coach. This will be offered on a needs basis only. Mentorship Both (core) All applicants will be expected to have a named These roles will not be Research Advisor (RA) who will provide oversight, remunerated. guidance, and mentorship. The RA will be expected to attend the training needs/scoping analysis at the commencement of the programme, and annual reviews of progress where appropriate. The RLP Research Advisor Role Descriptor document is available to download. https://www.soar-southampton.org/researchleaders-programme Access to support from UHS/UoS infrastructure (As appropriate) Both As indicated by an individual’s scope of RLP After enrolment individuals will be supported to identify an appropriate named career support mentor in addition. Including but not limited to: 1. The Southampton Academy of Research (SoAR) 2. Joint Research Function including: a. Grant application support b. Quality assurance and governance c. Finance d. Contracting 3. Southampton Centre for Research Engagement and Impact (SCREI) a. Public and Patient involvement b. Specialist research Communications 4. NIHR Southampton Clinical Research Facility (CRF) 5. NIHR Southampton Biomedical Research Centre (BRC) 6. NIHR Applied Research Collaboration Wessex (ARC Wessex) 7. Research Support Service South Central (RSS SC) (see above) 8. Southampton Clinical Research Delivery teams and support departments Met by infrastructure 4 Updated on 7/8/24 Figure 1: Schematic representation of Research Leaders Programme components 5 Updated on 7/8/24 Award Length Applications will be considered for up to a maximum of 36 months, and for no less than 20% WTE (irrespective of whether the person currently works full or part time). For Medical Consultants the allocation will be 2 PA. For other groups a greater WTE can be applied for but no more than 40% WTE. Applicants are advised to discuss their proposed WTE and Award Length with the RLP team, contactable via SoAR, prior to submitting an application. Eligibility The RLP programme is open to all healthcare professionals employed (who hold a substantive as opposed to honorary employment contract) by University Hospital Southampton NHS Trust, including nurses, midwives, pharmacists, allied health professionals, clinical scientists, and doctors (including Consultants, SAS, and Specialty Doctors). Individuals must have the explicit support of their manager for their application, who will agree to ensure arrangements are in place for backfill of RLP funded time. The manager must also agree that the individual will be released to attend all cohort meetings of the L2L Programme. Potential applicants are therefore advised to speak to their manager early to ensure this assurance can be provided in the application process. The panel will consider applications for award stream Group B (Clinical Academic) from individuals who are already registered for, and currently completing a programme of work towards an MD/PhD. The expectation for these individuals, is that the MD/PhD will be submitted early in the RLP fellowship, with a view to proceeding towards a competitive postdoctoral fellowship application (or similar) to sustain funding beyond the RLP. RLP awards are not appropriate as full MD/PhD fellowships but are intended to enable transition to post-doctoral research and secure future research funding. As such, RLP fellowships will not fund MD/PhD fees. Applicants in this position are advised to contact SoAR to clarify eligibility. Selection Procedure Applications will be reviewed by a panel composed of representatives from across the Trust and University. Detailed review of each application will focus on: 1. The potential for the applicant to become a health research leader of the future – the applicant will need to make a strong case as to why they would merit an RLP award. For example: Outputs from previous research experience and training relative to career stage and background, suitability, and commitment of applicant to a career as an independent researcher or leader of a research delivery team. 2. Suitability and scope of proposed objectives for RLP and the alignment of these objectives with Trust research objectives. (as set out in the UHS Clinical Strategy 2020-2025, and UHS Research For Impact Strategy 2023-2028). 3. Quality and relevance of training and development plans (research skills, experience, and research career). 4. Suitability and experience of research advisor in relation to the applicants proposed career pathway. 5. Quality of plans to support career progression and fund research activity beyond the award. Please note: Costings will be done by UHS Research Grants team after the shortlisting has taken place, so there is no requirement to ask your line managers or contact UHS Research Grants team. This will be done using the information from your application form, and access to the nominal roll. 6 Updated on 7/8/24 Conditions and Reporting Successful applicants will be expected to agree to the following conditions upon acceptance of the award. If these conditions are not met, then the award can be terminated at any stage by the UHS R&D Director or Clinical Director. 1. Comply with the funding requirements of the scheme throughout the duration of the award Individuals must remain backfilled during this period. Any proposed changes should be discussed and agreed in advance with the RLP team. Where individuals secure significant grant or fellowship income, this should be disclosed to the RLP team early, to facilitate discussion regarding the proportion and duration of RLP funded time alongside any other funded research time. 2. Engage with the core elements of the programme. Attendance at the L2L Leadership Gatherings is a mandatory component of an RLP award. Individuals who miss more than one session in an annual cycle will be asked to justify non-attendance. The RLP Oversight Board will then review whether these individuals can remain on the programme. 3. Annual progress report and review meeting. Individuals on the programme will also be expected to report outputs through the University of Southampton Pure system (award holders will be supported to gain access and training). 4. Provide evidence that the award holder’s line manager will support changes to the individual’s job plan which allow backfilled time to be devoted to the RLP. A line manager signature and support statement will be required both at the time of application, and upon acceptance of an award if successful. Capturing Return on Investment (ROI) resulting from the UHS Research Leaders Programme (RLP) Return on investment (ROI) has several facets– including, but not limited to: financial, academic, clinical, cultural, and reputational impact. RLP Award Holders are expected to communicate fully and in a timely way with the RLP team around the progress, and success, of any funding applications (including grants and fellowships). The RLP relies on the contributions of its Award Holders to shape the future design of the programme and monitor its impact. RLP Award Holders will be asked to provide examples and evidence of activities, supported by, or allied to the RLP which have had an impact on areas including, but not limited to: • Trust reputation • Safety, quality, efficiency, and effectiveness of patient care • Culture (aligned with Trust People Strategy) • Workforce (e.g., attracting good people to work at UHS, retention and sustainability of the workforce) As part of this activity, individuals will be asked to engage with a ‘Strategic Task’, which aims to raise the profile of research in their clinical area and provide evidence of how they are working towards research being a fully integrated part of day-to-day clinical care. 7 Updated on 7/8/24 Contractual obligations Maternity Leave, Parental Leave, extended Sick Leave or other period of prolonged absence RLP payments will continue throughout the absence with an extension to the end date of up to 12 months. The RLP Award Holder’s Manager would be informed of this decision and would be responsible, along with the RLP Award Holder, for liaising with the relevant Division accordingly. AfC banding promotions during RLP Award Consultant award holders already have salary scale progression automatically built into their RLP award at the outset. In line with this, any healthcare professional on an AfC contract, who applies for a promotion and is successful, would have the corresponding uplift to their salary as part of their RLP award. 8 Updated on 7/8/24
Url: /Media/Southampton-Clinical-Research/Downloads/RLP-Guidance-Notes-Cohort-5-Final.pdf

SHAPE Award Guide

Description: SHAPE FUNDING AWARDS Southampton Academy of Research (SoAR) in collaboration with Applied Research Collaboration (ARC Wessex) 1. Internship Awards 2. Transitional/ Bridging Awards 3. Post Doctoral Awards Year 2020/ 2021 Contents Introduction:........................................................................................................................................... 2 Internship Award.................................................................................................................................... 3 Eligibility:............................................................................................................................................. 3 How much is the Internship Award and how can the funding be used? ............................................ 3 Transitional/Bridging Award.................................................................................................................. 4 Eligibility .............................................................................................................................................. 4 How much is the Transitional/Bridging Award and how can the funding be used? .......................... 4 Post-Doctoral Awards ............................................................................................................................ 6 Eligibility:............................................................................................................................................. 6 How much is the Post-Doctoral Award and how can the funding be used? ...................................... 6 Application process:..................................................................................................................... 7 Evaluation: .................................................................................................................................. 7 Key dates:.......................................................................................... Error! Bookmark not defined. Closing date for applications: ....................................................................................................... 7 Notification of outcome: .............................................................................................................. 7 Award period:.............................................................................................................................. 7 Page 1 Introduction: Southampton Academy of Research (SoAR) in collaboration with Applied Research Collaboration (ARC Wessex) partnership continues to work on building capacity and capability in our clinical workforce. Our partnership aims to encourage people to develop their careers whilst applying their skills in practice to advance patient care. We have secured funding for 2020-2021 to support three separate funding awards. These awards support individuals who are either early in their clinical academic career and are thinking about doing postgraduate academic study at Master’s level and beyond, or seeking support for post doctoral activity. Each respective award offers support in preparation for applying for a further research training award. The Programme offers three separate awards: Internship Awards fund up to a maximum of £10,000 to support clinical academics who:  Demonstrate a keen interest in research  Are looking for an opportunity to prepare for doctoral level study Transitional Awards fund up to a maximum of £15,000 to support clinical academics who:  Are already studying at a minimum of a master’s degree or equivalent and are looking for an opportunity to prepare for a higher research degree and study Post-Doctoral Awards fund up to a maximum of £15,000 to support Post Doctoral clinical academics who:  Are looking to secure time and funding to enable them to continue with their research and work towards securing an award to continue their development, alongside meeting their clinical commitments. (Anticipated to submit a PhD in next 6 months OR able to show evidence of completion of doctorate) Each respective award offers researchers a unique opportunity to increase their research capability within the NHS with the aim to improve health and healthcare. We believe that by developing people with research aspirations they will have the potential to become leading clinical academics and independent researchers in the future. All successful applicants must have support from their line manager and additional support from their clinical academic supervisor. The objectives of the awards and future clinical academic aspirations should align with team/service clinical priorities and needs. The research should stand alongside ARC Wessex related themes; Ageing and dementia, Healthy communities, Long term conditions and a cross cutting theme-Workforce and health systems. Please refer to the accompanying ARC Wessex document for some guidance on their mission and themes. The awards are open to Allied Health Professionals, Nurses, Midwives, Pharmacists, Psychologists, Healthcare Scientists, and wider Dental Team Professions. Please continue to the respective award page for more information on eligibility and funding details. Page 2 Internship Award These awards offer the unique opportunity to help an applicant to tailor a structured, six month development plan. With support from their clinical academic supervisor, successful applicants will have an opportunity to shape their own bespoke educational programme tailored to suit their needs and aspirations. In addition, the applicant may participate in other activities which may include working with current researchers, visiting clinical research facilities, and/or attending research presentations and seminars. Eligibility: The awards are open to Allied Health Professionals, Nurses, Midwives, Pharmacists, Psychologists, Healthcare Scientists, and wider Dental Team Professions. To be eligible for one of these awards you will need to provide evidence that you have the following: 1. Current registration to practice in the UK with the appropriate regulatory and professional bodies 2. Hold a substantive full or part time contract with the University Hospital Southampton NHS Foundation Trust 3. One (1) year’s post-registration practice experience 4. Support from your line manager to undertake the internship 5. A keen interest and clear suitability for a research focused clinical academic career 6. Mentorship from a named clinical academic supervisor (identified by you) 7. The opportunity to develop links with an existing clinical research team (identified by you) 8. Ability to start the programme before the end of November 2020, and complete it on time Please note: Individuals already in receipt of a research grant from elsewhere are not eligible for this award. How much is the Internship Award and how can the funding be used? Each successful applicant will be awarded up to £10,000 to cover costs including: partial backfill salary, incidental costs, research and clinical supervision and formal education costs. Suggestions on how the budget can be spent are: 1. Salary backfill 2. Research project expenses 3. Academic supervision and formal teaching 4. Dissemination costs NB: Please get your spending plan checked by your finance teams prior to submission. The amount awarded will be paid directly to your NHS employer in November2020. Page 3 Transitional/Bridging Award These awards offer the unique opportunity to help an applicant to tailor a structured, six month development plan. With support from their clinical academic supervisor, successful applicants will have an opportunity to shape their own bespoke educational programme tailored to suit their needs and aspirations. In addition, the applicant may participate in other activities which may include working with current researchers, visiting clinical research facilities, and/or attending research presentations and seminars. Eligibility The awards are open to Allied Health Professionals, Nurses, Midwives, Pharmacists, Psychologists, Healthcare Scientists, and wider Dental Team Professions, who have received no formal long term training in research. (You are still eligible to apply if you had to complete a post graduate diploma or post graduate Master’s degree as part of your registration requirement). To be eligible, you will need to provide evidence that you have the following: 1. Current registration to practice in the UK with the appropriate regulatory and professional bodies 2. Hold a substantive full or part time contract with the University Hospital Southampton NHS Foundation Trust 3. One (1) year’s post-registration practice experience 4. Support from your employer to undertake the internship 5. A keen interest and clear suitability for a research focused clinical academic career 6. Mentorship from a named clinical academic supervisor (identified by you) 7. The opportunity to develop links with an existing clinical research team (identified by you) 8. Access to learning about research - this could include attending an academic module(s) or a short course(s) at a Master’s degree level or equivalent in an aspect of research methods or data analysis. 9. Ability to start the award before the end of November 2020, and complete it on time Please note: Individuals already in receipt of a research grant from elsewhere are not eligible for this award. How much is the Transitional/Bridging Award and how can the funding be used? Each successful applicant will be awarded up to £15,000 to cover costs including: partial backfill salary, incidental costs, research and clinical supervision and formal education costs. Suggestions on how the budget can be spent are: 1. Salary backfill 2. Research project expenses 3. Academic supervision and formal teaching 4. Dissemination costs Page 4 5. Attending an academic module(s) or a short course(s) at a Master’s degree level or equivalent NB: Please get your spending plan checked by your finance teams prior to submission. The amount awarded will be paid directly to your NHS employer in November 2020. Page 5 Post-Doctoral awards With an academic supervisor and clinical academic mentor, a successful applicant will have the opportunity to design a bespoke programme tailored to suit their specific clinical academic needs and aspirations around securing additional grant income (either a personal fellowship or project grant funding) and producing publications. The awards are only available on a part-time basis, through secondment. The research should align with ARC Wessex related themes: Ageing and dementia, Healthy communities, Long term conditions and a cross cutting theme-Workforce and health systems. Eligibility: The awards are open to Allied Health Professionals, Nurses, Midwives, Pharmacists, Psychologists, Healthcare Scientists, and wider Dental Team Professions. To be eligible for one of these awards you will need to provide evidence of the following:  Nurse, midwife or allied health professional with a substantive or honorary appointment with UHS  Have current registration to practice in the UK, with the appropriate regulatory and professional bodies  Confirmed by supervisor anticipated to submit PhD in next 6 months OR evidence of completion of doctorate  Support from line manager to take up the fellowship as a secondment  Intention to continue in a clinical academic career  Intention to work towards application for a fellowship e.g. NIHR Clinical Lectureship or other similar externally funded post doc fellowship  Proposed research programme demonstrates an interdisciplinary aspect, alignment with ARC Wessex, and includes details of the focus of research, outcomes to be achieved through the fellowship, and an outline learning and development plan.  Support of a named academic supervisor and mentorship from a named clinical academic Unfortunately, individuals currently in receipt of a grant related to education, training and career development from elsewhere are not eligible for this award. How much is the award and how can the funding be used? Each successful applicant will be awarded up to £15,000 to cover costs. Successful applicants will continue to be employed at their current AfC grade for the duration of the programme. Each successful applicant will be given up to a maximum of 6 months backfill, up to a maximum of 0.4WTE of salary costs at current AfC grade. (to accommodate up to AfC band 8B) Or 12 month backfill, up to a maximum of 0.2WTE of salary costs at current AfC grade. (to accommodate up to AfC band 8B) Page 6 Application process: Please submit a completed checklist (see respective Appendix 1) and all corresponding documentation to: soar@uhs.nhs.uk by midnight on 20th October 2020 NB: Please get your spending plan checked by finance teams prior to submission. Ensure that there is agreement that the funding can be managed by your employer across the financial year end if required. The amount awarded will be paid directly to your NHS employer this financial year. Evaluation: A full evaluation report will be required at the completion of the award period. Key dates: Closing date for applications: 20th October 2020, Midnight Notification of outcome: Tuesday 3rd November 2020 Award period: Internship Award- 6 months Transitional Award- 12 months Post Doctoral Award- 6 months or 12 months For further information, contact SoAR: SoAR@uhs.nhs.uk Page 7
Url: /Media/Southampton-Clinical-Research/Downloads/SHAPE-Award-Guide.pdf

BRC MRI Pump-priming Research Project application form_v1 2025 FINAL

Description: NIHR Southampton Biomedical Research Centre (BRC) Imaging Research Panel Application for an MRI Pump-priming Research Project Award The scheme The aim of this scheme is to support NIHR Southampton BRC Principal Investigators to develop competitive external funding applications for magnetic resonance (MR) imaging studies, leading to an increase in grants awarded to the BRC UHS/UoS partnership. The scheme is not intended for small stand-alone projects without a clear plan leading to larger more definitive studies. Applications without a clearly articulated external grant application outline, including specifics of grant-funding bodies and application deadline, are unlikely to be successful. The scheme will make use of the MR research imaging slots on the 3T MRI scanner. Every year, the University of Southampton purchases the use of a number of slots for use in the subsequent year, but a substantial proportion are not used. This scheme is intended to enable the BRC to access these slots and reimburse the University for the time, to help grow MR imaging research in Southampton. Due to the strategic aims of this scheme, applications should be supported by one of the BRC Themes: Nutrition, Lifestyle and Metabolism, Respiratory and Allergy, Data, Health and Society, Microbiology, Immunology and Infection, Perioperative and Critical Care, Candidate theme: Brain Health - Experimental and Applied Neuroscience, or Candidate theme: Cancer: Early Diagnosis, Targeted Treatment. Collaborations between Themes, between disparate disciplines across campus, and between the University of Southampton and University Hospital NHS Foundation Trust, are strongly encouraged. The awardee will be able to make use of 20 hours of MRI slots (in total), with each slot usually lasting 1 hour, over a maximum period of twelve months. Hence ideally ethical approval should be in place at the time of application. Applicants can apply for additional expenses (e.g. contrast) up to a maximum of £2,500. Applicants will also need to outline what image analysis or reporting is required – this may be supported by UHS MRI Physics and/or Radiology (if feasible), through other BRC funding (TBC), as will any UHS data management costs. Further rounds of the scheme will depend on this assessment. Eligibility NIHR Southampton BRC Principal Investigators, working within the Faculty of Medicine, and Faculty of Environmental and Life Sciences. Investigators in other Faculties, and investigators/research active staff employed by University Hospital Southampton NHS Foundation Trust are also encouraged to apply. Pre-award conditions Applicants must complete the BRC Research Imaging Proposal form as an initial Expression of Interest and submit it to Angela.Darekar@uhs.nhs.uk by 19th December 2025. Project feasibility will be assessed by MRI Physics and Radiology (via the Research Imaging Management Group, RIMG) regarding the technical aspects of the project (e.g. technical feasibility on the 3T scanner, protocol, analysis plan, duration). RIMG will review all proposals by 16th January 2026 and applicants will be granted approval to proceed by letter. Applications to this scheme will only be accepted if they are accompanied by a completed BRC Research Imaging Proposal form, accompanied by the approval letter. If approved by RIMG, the full BRC Imaging Research Panel application form (below) should be submitted to brc-applications@uhs.nhs.uk by 30th January 2026. Attachments required are: 1. the principal applicant’s three-page CV 2. fully completed and approved BRC Research Imaging Proposal form 3. RIMG approval letter 4. fully completed BRC Imaging Research Panel application form Post-award conditions When booking research MRI scans, priority is given to scan requests from externally funded studies. For this and other reasons, booking these (internally funded) scans will be subject to rules that may change during the course of the award. Scans can only be performed within the current UoS 3T MRI research sessions (Tuesday 8am-1pm, Thursday 3pm-8pm and Saturday 8am-1pm). The awardee may be approached by the BRC to provide feedback which will be used to assess the future potential of the scheme and inform its improvement. The awardee will need to submit two end-of-project reports to the BRC: one within one month, and the other within one year, of the end date of the project. Review process Applications will be internally peer reviewed. Priority will be given to applications of strategic importance to the BRC. The final decision will be made by BRC Imaging Research Panel. Timeline Applicants will be informed of the outcome of their application within approximately two weeks of the application deadline. Application Form: Details of Applicant(s) Principal Applicant Name (last name, first name, title): Academic Unit/Trust Department Current Post: Since: E-mail: Co-applicant Name: Academic Unit/Trust Department Current Post: Since: E-mail: Co-applicant Name: Academic Unit/Trust Department Current Post: Since: E-mail: Details of Current Proposal Title of Proposal: Expected start date: Completion date: Number of months: Statement of Proposed Research Your statement, on the following two pages, should include a full scientific and strategic justification. It should not exceed the boxes on the next two pages, using a Lucida Sans font no less than 10 point. The following are mandatory sections; other sections may be included: Background, hypothesis and aims Objectives and/or plan of investigation, including MRI Sample size justification of the pilot project Ethical approval plans Plan for consenting for, and managing, incidental findings Details of post-acquisition image analysis References Strategy for further funding Please attach a one page outline or abstract of the external funding proposal envisioned to arise from this pump-priming project. In this section, please: (1) explain why this project is essential to apply for external grant funding, (2) provide a clear plan for how data from this research will pump-prime additional substantive funding, including the names of sponsors, collaborators and schemes to be targeted, and when. Maximum: 250 words using a Lucida Sans font no less than 10 point. Alignment with NIHR Research Priorities. Maximum: 100 words, 10 point. Fit to BRC SMART objectives and/or research aims. Maximum: 100 words, 10 point. Please view BRC SMART objectives here: https://www.uhs.nhs.uk/Media/Southampton-Clinical-Research/Downloads/BRC-2022-2027-SMART-Objectives-ALL-Themes.pdf Collaborative nature of the proposal. Including names of people who will work on the project. Maximum: 100 words, 10 point. MR imaging time and costs: Please provide a full justification and breakdown of MR imaging time and costs. MR imaging time (i.e. as calculated from MRI protocol timings and sample size). This award will consist of a maximum of 20 hours of MR imaging time “in kind” only. It is mandatory to attach a completed BRC Research Imaging Proposal form to this application. Please specify in this subsection the number of MR imaging hours you are requesting, out of a maximum of 20. Any other costs, please list, in this section, all additional costs requested with this project to a maximum of £2,500 Add more rows as needed. Please copy this page if more space is needed. If additional costs are required on top, please list these and the funding source to support them. No other costs are involved: YES/ NO (strikethrough as required) Item Quantity Cost Funding source
Url: /Media/Southampton-Clinical-Research/Downloads/BRC-MRI-Pump-priming-Research-Project-application-form-v1-2025-FINAL.docx

BRC MRI Pump-priming Research Project application form_v1 FINAL 10.12.2024

Description: NIHR Southampton Biomedical Research Centre (BRC) Imaging Research Panel Application for an MRI Pump-priming Research Project Award The scheme The aim of this scheme is to support NIHR Southampton BRC Principal Investigators to develop competitive external funding applications for magnetic resonance (MR) imaging studies, leading to an increase in grants awarded to the BRC UHS/UoS partnership. The scheme is not intended for small stand-alone projects without a clear plan leading to larger more definitive studies. Applications without a clearly articulated external grant application outline, including specifics of grant-funding bodies and application deadline, are unlikely to be successful. The scheme will make use of the MR research imaging slots on the 3T MRI scanner. Every year, the University of Southampton purchases the use of a number of slots for use in the subsequent year, but a substantial proportion are not used. This scheme is intended to enable the BRC to access these slots and reimburse the University for the time, to help grow MR imaging research in Southampton. Due to the strategic aims of this scheme, applications should be supported by one of the BRC Themes: Nutrition, Lifestyle and Metabolism, Respiratory and Allergy, Data, Health and Society, Microbiology, Immunology and Infection, or Perioperative and Critical Care. Collaborations between Themes, between disparate disciplines across campus, and between the University of Southampton and University Hospital NHS Foundation Trust, are strongly encouraged. The awardee will be able to make use of 20 hours of MRI slots (in total), with each slot usually lasting 1 hour, over a maximum period of twelve months. Hence ideally ethical approval should be in place at the time of application. Applicants can apply for additional expenses (e.g. contrast) up to a maximum of £2,000. Applicants will also need to outline what image analysis or reporting is required – this may be supported by UHS MRI Physics and/or Radiology (if feasible), through other BRC funding (TBC), as will any UHS data management costs. Further rounds of the scheme will depend on this assessment. Eligibility NIHR Southampton BRC Principal Investigators, working within the Faculty of Medicine, and Faculty of Environmental and Life Sciences. Investigators in other Faculties, and investigators/research active staff employed by University Hospital Southampton NHS Foundation Trust are also encouraged to apply. Pre-award conditions Applicants must complete the BRC Research Imaging Proposal form as an initial Expression of Interest and submit it to Angela.Darekar@uhs.nhs.uk by 10th January 2025. Project feasibility will be assessed by MRI Physics and Radiology (via the Research Imaging Management Group, RIMG) regarding the technical aspects of the project (e.g. technical feasibility on the 3T scanner, protocol, analysis plan, duration). RIMG will review all proposals within 2 weeks (by 24th January 2025) and applicants will be granted approval to proceed by letter. Applications to this scheme will only be accepted if they are accompanied by a completed BRC Research Imaging Proposal form, accompanied by the approval letter. If approved by RIMG, the full BRC Imaging Research Panel application form (below) should be submitted to BRC@uhs.nhs.uk by 14th February 2025. Attachments required are: 1. the principal applicant’s three-page CV 2. fully completed and approved BRC Research Imaging Proposal form 3. RIMG approval letter 4. fully completed BRC Imaging Research Panel application form Post-award conditions When booking research MRI scans, priority is given to scan requests from externally funded studies. For this and other reasons, booking these (internally funded) scans will be subject to rules that may change during the course of the award. Scans can only be performed within the current UoS 3T MRI research sessions (Tuesday 8am-1pm, Thursday 3pm-8pm and Saturday 8am-1pm). The awardee may be approached by the BRC to provide feedback which will be used to assess the future potential of the scheme and inform its improvement. The awardee will need to submit two end-of-project reports to the BRC: one within one month, and the other within one year, of the end date of the project. Review process Applications will be internally peer reviewed. Priority will be given to applications of strategic importance to the BRC. The final decision will be made by BRC Imaging Research Panel. Timeline Applicants will be informed of the outcome of their application within approximately two weeks of the application deadline. Application Form: Details of Applicant(s) Principal Applicant Name (last name, first name, title): Academic Unit/Trust Department Current Post: Since: E-mail: Co-applicant Name: Academic Unit/Trust Department Current Post: Since: E-mail: Co-applicant Name: Academic Unit/Trust Department Current Post: Since: E-mail: Details of Current Proposal Title of Proposal: Expected start date: Completion date: Number of months: Statement of Proposed Research Your statement, on the following two pages, should include a full scientific and strategic justification. It should not exceed the boxes on the next two pages, using a Lucida Sans font no less than 10 point. The following are mandatory sections; other sections may be included: Background, hypothesis and aims Objectives and/or plan of investigation, including MRI Sample size justification of the pilot project Ethical approval plans Plan for consenting for, and managing, incidental findings Details of post-acquisition image analysis References Strategy for further funding Please attach a one page outline or abstract of the external funding proposal envisioned to arise from this pump-priming project. In this section, please: (1) explain why this project is essential to apply for external grant funding, (2) provide a clear plan for how data from this research will pump-prime additional substantive funding, including the names of sponsors, collaborators and schemes to be targeted, and when. Maximum: 250 words using a Lucida Sans font no less than 10 point. Alignment with NIHR Research Priorities. Maximum: 100 words, 10 point. Fit to BRC SMART objectives and/or research aims. Maximum: 100 words, 10 point. Please view BRC SMART objectives here: https://www.uhs.nhs.uk/Media/Southampton-Clinical-Research/Downloads/BRC-2022-2027-SMART-Objectives-ALL-Themes.pdf Collaborative nature of the proposal. Including names of people who will work on the project. Maximum: 100 words, 10 point. MR imaging time and costs: Please provide a full justification and breakdown of MR imaging time and costs. MR imaging time (i.e. as calculated from MRI protocol timings and sample size). This award will consist of a maximum of 20 hours of MR imaging time “in kind” only. It is mandatory to attach a completed BRC Research Imaging Proposal form to this application. Please specify in this subsection the number of MR imaging hours you are requesting, out of a maximum of 20. Any other costs, please list, in this section, all additional costs requested with this project to a maximum of £2,000 Add more rows as needed. Please copy this page if more space is needed. If additional costs are required on top, please list these and the funding source to support them. No other costs are involved: YES/ NO (strikethrough as required) Item Quantity Cost Funding source
Url: /Media/Southampton-Clinical-Research/Grants/Download/BRC-MRI-Pump-priming-Research-Project-application-form-v1-FINAL-10.12.2024.docx

BRC MRI Pump-priming Research Project application form_v1 FINAL 10.12.2024

Description: NIHR Southampton Biomedical Research Centre (BRC) Imaging Research Panel Application for an MRI Pump-priming Research Project Award The scheme The aim of this scheme is to support NIHR Southampton BRC Principal Investigators to develop competitive external funding applications for magnetic resonance (MR) imaging studies, leading to an increase in grants awarded to the BRC UHS/UoS partnership. The scheme is not intended for small stand-alone projects without a clear plan leading to larger more definitive studies. Applications without a clearly articulated external grant application outline, including specifics of grant-funding bodies and application deadline, are unlikely to be successful. The scheme will make use of the MR research imaging slots on the 3T MRI scanner. Every year, the University of Southampton purchases the use of a number of slots for use in the subsequent year, but a substantial proportion are not used. This scheme is intended to enable the BRC to access these slots and reimburse the University for the time, to help grow MR imaging research in Southampton. Due to the strategic aims of this scheme, applications should be supported by one of the BRC Themes: Nutrition, Lifestyle and Metabolism, Respiratory and Allergy, Data, Health and Society, Microbiology, Immunology and Infection, or Perioperative and Critical Care. Collaborations between Themes, between disparate disciplines across campus, and between the University of Southampton and University Hospital NHS Foundation Trust, are strongly encouraged. The awardee will be able to make use of 20 hours of MRI slots (in total), with each slot usually lasting 1 hour, over a maximum period of twelve months. Hence ideally ethical approval should be in place at the time of application. Applicants can apply for additional expenses (e.g. contrast) up to a maximum of £2,000. Applicants will also need to outline what image analysis or reporting is required – this may be supported by UHS MRI Physics and/or Radiology (if feasible), through other BRC funding (TBC), as will any UHS data management costs. Further rounds of the scheme will depend on this assessment. Eligibility NIHR Southampton BRC Principal Investigators, working within the Faculty of Medicine, and Faculty of Environmental and Life Sciences. Investigators in other Faculties, and investigators/research active staff employed by University Hospital Southampton NHS Foundation Trust are also encouraged to apply. Pre-award conditions Applicants must complete the BRC Research Imaging Proposal form as an initial Expression of Interest and submit it to Angela.Darekar@uhs.nhs.uk by 10th January 2025. Project feasibility will be assessed by MRI Physics and Radiology (via the Research Imaging Management Group, RIMG) regarding the technical aspects of the project (e.g. technical feasibility on the 3T scanner, protocol, analysis plan, duration). RIMG will review all proposals within 2 weeks (by 24th January 2025) and applicants will be granted approval to proceed by letter. Applications to this scheme will only be accepted if they are accompanied by a completed BRC Research Imaging Proposal form, accompanied by the approval letter. If approved by RIMG, the full BRC Imaging Research Panel application form (below) should be submitted to BRC@uhs.nhs.uk by 14th February 2025. Attachments required are: 1. the principal applicant’s three-page CV 2. fully completed and approved BRC Research Imaging Proposal form 3. RIMG approval letter 4. fully completed BRC Imaging Research Panel application form Post-award conditions When booking research MRI scans, priority is given to scan requests from externally funded studies. For this and other reasons, booking these (internally funded) scans will be subject to rules that may change during the course of the award. Scans can only be performed within the current UoS 3T MRI research sessions (Tuesday 8am-1pm, Thursday 3pm-8pm and Saturday 8am-1pm). The awardee may be approached by the BRC to provide feedback which will be used to assess the future potential of the scheme and inform its improvement. The awardee will need to submit two end-of-project reports to the BRC: one within one month, and the other within one year, of the end date of the project. Review process Applications will be internally peer reviewed. Priority will be given to applications of strategic importance to the BRC. The final decision will be made by BRC Imaging Research Panel. Timeline Applicants will be informed of the outcome of their application within approximately two weeks of the application deadline. Application Form: Details of Applicant(s) Principal Applicant Name (last name, first name, title): Academic Unit/Trust Department Current Post: Since: E-mail: Co-applicant Name: Academic Unit/Trust Department Current Post: Since: E-mail: Co-applicant Name: Academic Unit/Trust Department Current Post: Since: E-mail: Details of Current Proposal Title of Proposal: Expected start date: Completion date: Number of months: Statement of Proposed Research Your statement, on the following two pages, should include a full scientific and strategic justification. It should not exceed the boxes on the next two pages, using a Lucida Sans font no less than 10 point. The following are mandatory sections; other sections may be included: Background, hypothesis and aims Objectives and/or plan of investigation, including MRI Sample size justification of the pilot project Ethical approval plans Plan for consenting for, and managing, incidental findings Details of post-acquisition image analysis References Strategy for further funding Please attach a one page outline or abstract of the external funding proposal envisioned to arise from this pump-priming project. In this section, please: (1) explain why this project is essential to apply for external grant funding, (2) provide a clear plan for how data from this research will pump-prime additional substantive funding, including the names of sponsors, collaborators and schemes to be targeted, and when. Maximum: 250 words using a Lucida Sans font no less than 10 point. Alignment with NIHR Research Priorities. Maximum: 100 words, 10 point. Fit to BRC SMART objectives and/or research aims. Maximum: 100 words, 10 point. Please view BRC SMART objectives here: https://www.uhs.nhs.uk/Media/Southampton-Clinical-Research/Downloads/BRC-2022-2027-SMART-Objectives-ALL-Themes.pdf Collaborative nature of the proposal. Including names of people who will work on the project. Maximum: 100 words, 10 point. MR imaging time and costs: Please provide a full justification and breakdown of MR imaging time and costs. MR imaging time (i.e. as calculated from MRI protocol timings and sample size). This award will consist of a maximum of 20 hours of MR imaging time “in kind” only. It is mandatory to attach a completed BRC Research Imaging Proposal form to this application. Please specify in this subsection the number of MR imaging hours you are requesting, out of a maximum of 20. Any other costs, please list, in this section, all additional costs requested with this project to a maximum of £2,000 Add more rows as needed. Please copy this page if more space is needed. If additional costs are required on top, please list these and the funding source to support them. No other costs are involved: YES/ NO (strikethrough as required) Item Quantity Cost Funding source
Url: /Media/Southampton-Clinical-Research/Downloads/BRC-MRI-Pump-priming-Research-Project-application-form-v1-FINAL-10.12.2024.docx

Targeting-Shared-Mechanisms-Call-1

Description: Call for Applications: Targeting shared mechanisms in immune-mediated inflammatory diseases Introduction and rationale There are more than 80 autoimmune conditions affecting over four million people in the UK. Research into immune-mediated inflammatory conditions is often pursued in a disease-specific manner, according to clinical presentation, and focusing on later stages of disease. Emerging evidence suggests there are similarities across autoimmune diseases in risk factors, immunological and pathological processes, suggesting there are significant opportunities to drive forward the development of new treatments by encouraging research that works across, or learns from, other autoimmune conditions. In May 2021, the Chernajovsky Foundation and Connect Immune Research brought the research community together to discuss targeting shared mechanisms in immune-mediated inflammatory diseases, and to catalyse new collaborations, research ideas and proposals in the area. At this meeting the immune condition research community explored and further defined priority topics in this area, as well as identifying gaps and opportunities for future research. The Chernajovsky Foundation and Connect Immune Research have come together as a consortium to address these priority topics. Examples of the topics of interest are presented below in “Areas of Interest” however the scope of this call is not limited to these areas. We will fund “pilot” grants aimed at quickly developing proof of principle new treatments for multiple autoimmune conditions, by targeting pathways common in autoimmunity. The funding will enable multidisciplinary groups of researchers to develop and progress innovative cross-disease research questions closer to benefits for people with autoimmune conditions. It is envisaged that successful candidates whose projects demonstrate the most promising outputs will be able to compete for further funding at a scale to quickly develop their research for patient benefit. Call Overview Funders Application deadline Budget available Project duration The Chernajovsky Foundation and Connect Immune Research 4pm (BST), Wednesday 13th October, 2021 Up to £100,000 Up to 12 months 01 Study Design Principles  Applications must show how the outputs from the award could lead to benefit for patients from more than one autoimmune condition.  Highly innovative, potentially risky research ideas are expected.  Translational research only, defined here as: Research that seeks to advance and apply discoveries from basic discovery research and/or clinical findings, through preclinical studies and towards clinical studies and trials. Development of drugs, diagnostics and devices are welcomed.  Milestone driven, meaning projects should focus on rapid advancement and will be required to report on a key performance indicator milestone within 6 months of project commencement.  The proposed project can include a discovery stage (no more than 4 months), however the majority of the project should be to demonstrate proof of principle.  The application should outline, if the proposed research project is successful, how the research could be translated into patient benefit in a second funding stage by briefly describing the plan for executing a translational research study or developing any resulting technologies.  The proposed research project should be collaborative, connecting immune researchers with expertise in a number of autoimmune conditions; and/or from more than one institution; and/or team members from different stages of the translational pathway, such as preclinical, translational and clinician scientists (collaborations with industrial partners are welcome but not necessary at this stage).  The lead applicant must be based in the UK and should have international recognition. They would ideally have previous experience of leading, or demonstrable ability to lead, multi-disciplinary research.  Meaningful patient and public involvement (PPI) is expected at all stages of application and award, with applications expected to seek and take into consideration the views and needs of people with autoimmune conditions. Support for PPI is available from the funders (see below). Areas of Interest Applicants should consider, but NOT be limited to, the example areas of interest, gaps and opportunities for future research that were identified by representatives of the autoimmunity research community in a workshop held in May 2021:  Revisit interferon response and autophagy to define disease drivers of these pathways for new interventions  Leveraging single cell and epigenetic analyses to determine new therapeutic concepts  Look beyond professional immune cells to the tissues to break the efficacy ceiling  Immune-neuronal bidirectional signalling in health and disease and new opportunities for intervention  Harnessing new understanding of the interplay between the gut microbiome, gut immune system and enteric nervous system Outputs from the Study  A report detailing the progress made mid-way through the project. Page 2 of 5  Submission of a final report describing the project undertaken, results and the next steps for developing the research (if any).  A presentation of results to be delivered to the Oversight Committee upon completion of the project. Outcomes from the Study  On completion the most promising projects will be invited to apply for more funding in the second phase, which may include funding for developing new methodologies or clinical trial designs potentially using repurposed current therapeutics. Application and assessment process Who can apply and what you can apply for The award will be for up to £100,000, up to 12 months with an expected starting date by Spring/Summer 2022. This call is open to teams affiliated to a university, hospital or other recognised research institution worldwide, but the lead applicant must be based at a UK institution. The application should be led by an independent lead applicant with an internationally competitive research track record. They would ideally have previous experience of leading, or demonstrable ability to lead, multi-disciplinary research. Although the applications must have a UK based lead applicant, collaborations with international and industrial partners are welcome. For information about industrial collaborations please read the guidelines from the AMRC. The proposed research project should be collaborative, connecting immune researchers with expertise in a number of autoimmune conditions; and/or from more than one institution; and/or team members from different stages of the translational pathway, such as preclinical, translational and clinician scientists (collaborations with industrial partners are welcome but not necessary at this stage). Before completing the application form please read the associated guidance documentation. Research involving patients, service users, care professionals or volunteers, or their organs, tissue or data must obtain Research Ethics Committee (REC) approval before any work can start. For any pre-clinical studies using animal models, the Funders are fully committed to the 3Rs principles (Replace, Reduce, Refine) and all our research abides by rules set out by the Home Office. Under this system, animals can only be used when there is no alternative. We are members of the Association of Medical Research Charities and sign up to their position on animal research. How will applications be assessed Applications will be assessed for eligibility to the call and then will undergo expert peer and lay review. Assessment by lay people forms a key part of the review process, as such, applicants should carefully consider the use of non-scientific language in the application form. Applicants will be invited to respond to review comments in a Rebuttal stage. Depending on the number of applications, the funders may undertake a triage stage based on reviewer feedback prior to the final panel meeting. Page 3 of 5 A panel of scientific experts and lay people will recommend an award. The criteria used to assess applications include:  Relevance to the development of collaborative strategies leading to the identification of treatments for autoimmune and immune mediated diseases.  Innovative and high-quality science  Potential for long term impact on quality of life for people currently living with autoimmune or immune mediated conditions.  Involvement of people with autoimmune or immune mediated conditions in the proposed research.  Clear description and justification of how the project methodology will address the proposed study design and deliver the required outcomes.  Strength and make-up of the research team, including multidisciplinary collaboration and proposed management arrangements.  Applicants’ track record and ability to deliver the proposed research, and facilities to conduct the proposed research  Feasibility, the potential to deliver the stated outcomes within the timescales and budget  Value for money Patient and Public Involvement We believe that involving people affected by medical conditions strengthens the quality and relevance of medical research. We encourage applicants to consider how the quality, feasibility or practicality of their proposal could be improved by involving people affected by immune conditions in its development or oversight. It is important to write a clear non-scientific summary because people affected by autoimmune conditions are involved in the review process. Please see the Applicant Guidance for further information. For further information about patient and public involvement in your application, please email patientinsight@versusarthritis.org. There are also useful resources on INVOLVE’s website: www.invo.org.uk. Contact details and how to submit an application To submit a proposal on this topic, complete the online application form at Versus Arthritis grant management system. Deadline for application Notification of Award Project Start 4pm (BST), Wednesday 13th October 2021 Early 2022 By Spring/Summer 2022 Enquiries Please contact Versus Arthritis email: research@versusarthritis.org. Page 4 of 5 Funder information (1) The Lorna and Yuti Chernajovsky Biomedical Research Foundation registered as a charity in England and Wales no.1184405 whose office is at PO Box 1198, Whitstable, Kent, CT5 9DW, UK (“the Chernajovsky Foundation”); (2) Connect Immune Research, a group of organisations that includes: a. Alopecia UK registered as a charity in England and Wales no. 1111304 and in Scotland no. SCO44702 whose registered office is at 10-12 Commercial Street, Shipley, West Yorkshire BD18 3SR (“Alopecia UK”); b. Bowel Research UK registered as a charity no. 1186061 and incorporated and registered in England and Wales as a company no. CE019377 whose registered office is c/o The Royal College of Surgeons, 35-43 Lincoln’s Inn Fields, London WC2A 3PE (“Bowel Research UK”); c. Coeliac UK is a charity registered in England & Wales (1048167) and in Scotland (SC039804) and a company limited by guarantee in England and Wales (3068044) whose registered office 3rd Floor, Apollo Centre, Desborough Road, High Wycombe, Buckinghamshire, HP11 2QW (“Coeliac UK”); d. the Juvenile Diabetes Research Foundation incorporated and registered in England and Wales as a private company limited by guarantee, company number 2071638, registered as a charity in England and Wales no. 295716 and in Scotland no. SC040123 and whose registered office is at 17/18 Angel Gate, City Road, London EC1V 2PT (“JDRF UK”); e. the British Society for Immunology incorporated and registered in England and Wales as a private limited company by guarantee, company number 03005933, registered as a charity in England and Wales no. 1043255 and in Scotland no. SC047367 whose temporary registered office is at Devonshire House, 60 Goswell Road, London, EC1M 7AD (“the BSI”); f. the Multiple Sclerosis Society incorporated and registered in England and Wales as a private company by limited guarantee, company number 07451571, registered as a charity in England and Wales no. 1139257 and in Scotland no. SC041990 whose registered office is at 10 Queen Street Place, London EC4R 1AG (“the MS Society”); g. The Psoriasis and Psoriatic Arthritis Alliance is incorporated and registered in England and Wales as a private company by limited by guarantee, company number 06656347, registered as a charity in England and Wales no. 1118192 and whose registered office is at Acre House, 11-15 William Road, London NW1 3ER (“the PAPAA”); h. Versus Arthritis incorporated and registered in England and Wales as a private company limited by guarantee, company number 490500, registered as a charity in England and Wales no. 207711 and in Scotland no. SC041156 whose registered office is at Copeman House, St Mary’s Court, St Mary’s Gate, Chesterfield S41 7TD (“Versus Arthritis”), (together CIR). Page 5 of 5
Url: /Media/Southampton-Clinical-Research/Downloads/Targeting-Shared-Mechanisms-Call-1.pdf

Expression of interest form

Description: Fellowship Expression of Interest This Expression of Interest (EOI) form should be completed by anyone considering an application for an external fellowship, at any level, through either: * University of Southampton’s Faculty of Medicine or School of Health Sciences (Faculty of Environmental and Life Sciences), or * University Hospital Southampton, or * other local NHS Trust The information you provide will enable your Faculty/School and Trust to guide you and, where appropriate, to provide ongoing support for your application and project. Fellowship Expression of Interest Process Please complete the form as fully as possible; there will be later opportunities to resolve unknown details. Return the form with a short academic CV to the proposed employing organisation, i.e. the proposed host organisation for the fellowship. (In the case of Trusts other than UHS, please send to University of Southampton, regardless of employing organisation.) * University Hospital Southampton: researchgrants@uhs.nhs.uk * University of Southampton or other NHS Trust: * Faculty of Medicine: biomedicalresearch@soton.ac.uk (resmed) or * School of Health Sciences (Faculty of Environmental and Life Sciences): hsapp@soton.ac.uk The EOIs will be reviewed by either the relevant University fellowship champion(s) or the Director of Southampton Academy of Research (SoAR) for University Hospital Southampton hosted fellowships. The reviewer(s) will suggest appropriate next steps and identify where applicants can find suitable support. Important Information: * To help coordinate support, the applicant’s information may be shared between a Faculty/School and a Trust. * If you DO NOT want your EOI to be shared with a particular organisation please highlight this in your email when you submit the EOI. * The Faculty/School and University Hospital Southampton aim to provide support provided the EOI is submitted at least 12 weeks before the funder deadline. * Developing a robust proposal takes a long time and applicants are encouraged to submit an EOI as early as possible. Applicants should allow a minimum of six months or, ideally, a year for writing the application, in order to take full advantage of all possible training, mentoring and support available. * The Faculty of Medicine, the School of Health Sciences and the University Hospital Southampton reserve the right not to approve applications from applicants who have not followed this process. Fellowship Expression of Interest Form Applicant Information Applicant Name Click or tap here to enter text. Career Stage Pre-doctoral/Training (for PhD students) / Early Career / Transition to independence / Transition to leadership / Established leader Click or tap here to enter text. Current employer University of Southampton or named NHS Trust Click or tap here to enter text. Current Faculty/School (UoS) or Division (Trust) Click or tap here to enter text. Current job/role(s) Title of current post Click or tap here to enter text. Select relevant role(s) Clinical Research Education Current line manager Please also confirm that you have discussed your intention to apply for a fellowship with your current line manager Name: Job title: Contact details: Fellowship details Proposed funder and scheme (if known) Proposed funder: Proposed scheme: Are you considering any other funders/schemes? If yes, who? Anticipated submission date (if known) Click or tap to enter a date. Duration of proposed fellowship and % of your time it will take (wte) Click here to enter text. Details of any additional academic institutions to be involved Click or tap here to enter text. Proposed Supervisor/Mentor /Scientific advisor If you can, please provide names of supervisors/mentors/scientific advisors you think might potentially play a role in your fellowship application Click or tap here to enter text. Proposed working title of research project Click or tap here to enter text. For external applicants only (i.e. not UoS, UHS or other local NHS Trust): Why have you chosen to undertake your Fellowship in Southampton? suggested word count: 200 words Click or tap here to enter text. Fellowship host information Please complete only the green column if University of Southampton will employ you during your proposed fellowship - University of Southampton will be your anticipated employer. Complete only the blue column if University Hospital Southampton or another NHS Trust will employ you during your proposed fellowship – NHS will be your anticipated employer. If your fellowship requires both an academic host (university of Southampton) and a clinical Trust partner (for example the NIHR Integrated Clinical Academic fellowships scheme, including Pre-doctoral Clinical Academic Fellowships) then please complete both green and blue columns. Anticipated employer – choose either UoS or NHS Trust unless your identified scheme requires both University of Southampton Click or tap here to enter text. NHS Trust (specify) Click or tap here to enter text. UoS Faculty / NHS Trust Division Choose an item. Choose an item. UoS School / NHS Care group Select: Choose an item. Care group (specify) Click or tap here to enter text. Anticipated Faculty/School research group or theme Specify: Click or tap here to enter text. Have you discussed your intention to apply for a fellowship with the head of research group or theme lead? Choose an item. Not applicable for Trust If you have any feedback regarding this form and the EOI process, please send to biomedicalresearch@soton.ac.uk or researchgrants@uhs.nhs.uk Expression of Interest Form for Fellowships July 2019_final
Url: /Media/Southampton-Clinical-Research/Grants/Download/Expression-of-interest-form.docx

Current funding calls

Description: Auto Generated Title Here you can find new grant funding calls from various funders. Links on the right will take you directly to other calls with specific key funders. Keep up-to-date with COVID-19 funding calls and resources The Health Research Authority is publishing details about all approved COVID-19 research studies, within their dedicated COVID-19 section. More information New research priorities identified for aerosol generating procedures related to COVID-19 New funding opportunities are likely to result from the identification of a new set of research priorities relating to the COVID-19 pandemic. Details will be published here as they are made available. Five new research priorities have been identified through the NIHR expert review process, with the purpose of providing evidence to understand and assess aerosol generation and the infective risk associated with individual AGPs as well as broader questions about airborne transmission of COVID-19 in healthcare settings. Understanding the fundamental aerobiology Including virus distribution and viability in airborne particles. Risk factors for transmissibility Understanding and quantifying the risk of transmissibility across multiple domains (including patient, procedure, environment, pathogen and healthcare professional factors) in order to generate a clinically applicable risk model. Mitigating precautions and their components Identifying which mitigating precautions are important and how they work: to include clinical efficacy testing of PPE, environmental measures (e.g. ventilation, filtration), and other barrier devices. Transmission of COVID-19 and other pathogens Investigating the contribution of inhalation versus inoculation for infection risk from AGPs and other healthcare interventions. Understanding infective risk perception, behaviours and acceptability of mitigation strategies This will include diverse groups of healthcare workers, patients and the public. More information EPSRC - healthcare technologies investigator-led grant Funder: Engineering and Physical Sciences Research Council Closing date: n/a - OPEN CALL Healthcare technologies investigator-led research grants are for researchers at UK higher education institutions, research council institutes, UKRI-approved independent research organisations and NHS bodies. We strongly encourage collaboration with relevant healthcare professionals, other researchers, industry, the public sector and other relevant partners. We are looking for researchers in engineering, physical sciences, information and communications technologies (ICT) and mathematical sciences who want to apply their expertise to healthcare challenges. Projects can range in size from small short-term grants to multi-million-pound research programmes lasting several years. There is no limit on the size of the grant or length of the project. We will award 80% of the full economic costs of the project, and your organisation must agree to find the balance. More information UKRI - addressing limitations in manufacturing nucleic acid therapeutics Funder: UKRI Closing date: n/a - OPEN CALL Apply for funding to set up a research consortium addressing challenges in the manufacture of nucleic acid therapeutics. Current manufacture challenges include but are not limited to: scale of production product purity, stereochemistry and reproducibility sustainable production novel chemistries synthesis efficiency analytical oligonucleotide characterisation. The consortium can include academic and industrial organisations in the UK and abroad. The lead organisation must be UK-based. More information NIHR - NICE rolling call for research studies addressing NICE research recommendations Funder: NIHR Closing date: various, see below The NIHR research programmes (EME, HTA, PHR and HS&DR) are interested in receiving applications to meet recommendations in research identified in NICE guidance published from 2015 onwards (for the purposes of this call, NICE guidance includes the following: clinical, social care, public health, technology appraisals, interventional procedures and diagnostics). Proposals must be within the remit of one of the participating NIHR research programmes and the primary outcome measure must be health related. Proposals must be within the remit of at least one of the following participating NIHR Programmes. However, applications which span the remit of one or more programme are welcome. Health Technology Assessment (deadline 05 January 2022) Public Health Research (deadline: 30 November 2021) Sight Research UK - translational research award Funder: Sight Research UK Closing date: 30 November 2021 Sight Research UK funds pioneering research into the causes of eye disease, in order to develop better prevention methods and more effective treatments for children and adults. The Translational Research Award supports research projects with a clearly defined pathway to achieving patient benefit. Its goal is to help to accelerate the translation of scientific findings to the early stages of development of new therapies, devices, and diagnostics. Sight Research UK welcomes projects that have robust commercial potential, likely to attract large scale follow-on funding from other charitable, statutory or industry funders. Eligible projects must: Be based on unmet clinical need. Aim to generate lead candidates for therapeutic applications. Be relevant to and highly promising in the clinical setting (these are not early stage, proof of concept studies, instead they have already shown that the idea might be used as therapy in man). Be focused on assessing properties such as potency, efficacy, selectivity, or bioavailability of compounds identified by previous research as potentially strong candidates for therapeutic applications. Have a clear pathway to apply for funding such as the MRC Confidence in Concept, MRC Development Pathway Funding Scheme type funding and other similar funding schemes. More information NIHR Public Health Research Programme - researcher-led workstream Funder: NIHR Closing date: 30 November 2021 The Public Health Research (PHR) Programme funds research to generate evidence to inform the delivery of non-NHS interventions, intended to improve the health of the public, and reduce inequalities in health. The Public Health Research Programme are accepting stage 1 applications to their researcher-led workstream. More information NIHR Public Health Research Programme - dementia research call Funder: NIHR Closing date: 30 November 2021 This National Institute for Health Research (NIHR) call invites proposals for dementia research to address important health and social care questions. Research could involve any aspect of prevention, diagnosis, treatment, support or care, and related health and social care services. Applications which involve investigators spanning a range of specialties are encouraged and partnership with national charities welcomed. The HTA and EME programmes are also featuring this research area - see below 7 December and 5 January. More information British Geriatrics Society - specialist registrar research start-up grants Funder: BGS Closing date: 30 November 2021 The British Geriatrics Society Specialist Registrar Research Start-Up Grant scheme provides grants to individuals who want to get a research project started. The aim is to allow young doctors to follow through ideas at relatively short notice, to enable advantage to be taken of unique or rare opportunities, and to provide short-term assistance to speculative and innovative research that may be at an early stage. The grants may support a complete project or, where appropriate, support a pilot study to enable an application for external project grant support to be made. The grants are eligible for National Institute for Health Research (NIHR ) non-commercial partner status. More information NIHR Development and Skills Enhancement Award Round 8 Funder: NIHR Closing date: 30 November 2021 The Development and Skills Enhancement Award (DSE) provides a maximum of 1 year of funding for post-doctoral NIHR Academy Members to gain skills and experience for the next phase of their research career. As an applicant you will be required to demonstrate the new skills and experience you hope to gain through the award, and how it will benefit your future career in research. More Information NIHR PHR Programme 21/560 - James Lind Alliance priority setting partnerships rolling call Funder: NIHR Closing date: 30 November 2021 The Public Health Research (PHR) Programme funds research to generate evidence to inform the delivery of non-NHS interventions, intended to improve the health of the public, and reduce inequalities in health. The JLA Priority Setting Partnerships facilitate patients, carers and clinicians to work collaboratively to identify research priorities in particular areas of health and care. Their aim is to ensure that health research funders are aware of the issues that are important to the people who need to use the research in their daily lives. The NIHR PHR programme recognises the importance of the research priorities identified by the James Lind Alliance Priority Setting Partnerships and is interested in receiving high-quality applications which address them More information MRC - advancing adolescent mental health and wellbeing research Funder: Medical Research Council Closing date: 1 December 2021 Apply for funding to help improve research in the field of ‘ adolescence, mental health and the developing mind ’ through: methodological innovation capability building This opportunity will support projects that help researchers in delivering more relevant, valid, reproducible, mechanistically informed, multi-level and translationally scalable research in adolescent mental health over the next decade. Outputs from these projects may also allow new research questions to be investigated. Proposals should: address a clear area of unmet need with regard to existing research methods, concepts, tools or measures identify innovative new approaches for conducting mental health and wellbeing research with adolescents. More information NIHR - Health Technology Assessment Programme, commissioned workstreams Funder: NIHR Closing date: 1 December 2021 21/532 Intensive Interaction for children and young people with profound and multiple learning disabilities 21/534 Surgical management of successfully reduced incarcerated inguinal hernia in children 21/535 Follow-up strategy after radical treatment for prostate cancer 21/536 Sodium bicarbonate in neonatal care 21/537 Neuroendoscopic lavage for preterm babies with post-haemorrhagic ventricular dilatation 21/538 Benefits and harms of reduced dose oral isotretinoin in the management of acne vulgaris 21/539 Benefits and harms of maintenance therapy for refractory acne vulgaris or previous relapses by reduced dose isotretinoin regimens 21/540 Pharmacological treatments for low back pain or sciatica 21/542 Medication to manage sexual preoccupation in sex offenders 21/552 Microsuction compared with irrigation to remove earwax Diabetes UK - small grants and project grants Funder: Diabetes UK Closing date: 1 December 2021 Diabetes UK aims to improve lives through pioneering research into all forms of diabetes and diabetes-related complications. The work they support helps us understand the causes of diabetes, bring about life-changing breakthroughs in care, treatment and prevention and brings us closer to a cure. The following calls are open for application: Project grants : For high quality, hypothesis driven diabetes research projects, lasting up to five years and costing less than £ 500,000. Current research priority areas are: (1) New glucose monitoring technologies in inpatient care; (2) Understanding the pathogenesis of diabetes that develops atypically, or in minority populations Deadline for applications: 01 December 2021 Early-Career Small Grants : supports early-career basic scientists and members of Allied Health Professions to undertake small research projects related to diabetes. The scheme will enable scientists at an early stage in their career to develop their work and go on to obtain additional grant funding from other organisations. Nurses, pharmacists and members of the Allied Health Professions who meet the eligibility criteria may apply through this scheme. Deadline for applications: 01 December 2021 Diabetes UK & Great Foundations - addressing the issues in foot care which lead people with diabetes developing foot conditions Funder: Diabetes UK and Great Foundations Closing date: 1 December 2021 Diabetes UK and Great Foundations are inviting proposals addressing the issues which lead to people with diabetes developing ulcers or other diabetes-related foot conditions and these then progressing further. Preventing foot ulcers, amputations and other severe foot complications in people with diabetes is a key priority for the Diabetes Research Steering Group. There is a clear need for innovative approaches to do this, but these need to consider the findings of previous studies and address factors in foot care which may have previously not been subject to research. These include social factors which present significant barriers to care or treatment, the difficulty people with neuropathy have in detecting and adapting to foot conditions and the need for effective and rapid referrals for foot care when it is needed. More Information Versus Arthritis & MSK TRC - accelerating new treatments Funder: NIHR/Versus Arthritis Closing date: 1 December 2021 As part of the UK Musculoskeletal Translational Research Collaboration (MSK TRC) we are launching the second call for research projects focused on mechanistic experimental/translational medicine studies in humans across the areas of prevention, diagnosis or treatment that are aimed at priming the next transitional step. More information NIHR - Research Professorships, round 12 Funder: NIHR Closing date: 1 December 2021 The NIHR Research Professorships aim to fund research leaders of the future to promote effective translation of research and to strengthen health, public health and care research leadership at the highest academic levels. The scheme is open to all professions and all Higher Education Institutions (HEI), in partnership with NHS organisations, or other providers of health, public health and/or care services based in England, to nominate health, public health and social care researchers and methodologists with an outstanding research record of clinical and applied health research and its effective translation for improved health. Candidates must demonstrate they are on a steep career trajectory to become a research leader having spent no more than five years at their current level of seniority at the time of application. More information Davos Alzheimer's Collaborative - increasing cognitive assessment rates for older adults Funder: Davos Alzheimer's Collaborative Closing date: 1 December 2021 The Davos Alzheimer ’ s Collaborative (DAC) is funding innovators who can increase cognitive assessment rates for older adults. The proposed approach should aim to increase the percentage of patients age 65+ who are provided with a standardized cognitive assessment in selected health system(s) or implementation site(s). It should indicate which health system(s) or other implementation partner(s) your team plans work with. It can utilize any cognitive assessment solution, technology or tool with clear evidence of efficacy and potential for sustainability. DAC is agnostic on the exact mechanism for cognitive assessment. Teams can develop a novel solution or implement an existing solution. More information Psoriasis Association: Research Grants Funder: Psoriasis Association Closing date: 3 December 2021 The Psoriasis Association will consider applications that have clear relevance to its aim 'to promote and fund research into the causes, nature and care of psoriasis and to publish and disseminate the results of that research'. The Psoriasis Association offers the following: PhD studentships : Supports the training of graduate students leading to the presentation of a PhD Cecil King Memorial Award : For projects where the principal researcher is under 35 years of age, or within the first five consecutive years, at the time of application, of either their first permanent independent academic research post or a named limited-tenured/fixed-term academic research post, obtained in open competition More Information Southampton Academy of Research - training awards Funder: NIHR SoAR Closing date: 14 December 2021 SoAR funding awards 2021/2022 are now open for applications: Internship award - 6 months Transitional award - 12 months Post doctoral award - 6 or 12 months Further information is available by email NIHR - efficiency and mechanism evaluation programme - new commissioned calls Funder: NIHR Closing date: 7 December 2021 The Efficacy and Mechanism Evaluation (EME) Programme funds ambitious studies evaluating interventions with potential to make a step-change in the promotion of health, treatment of disease and improvement of rehabilitation or long-term care. Within these studies, EME supports research in the mechanisms of diseases and treatments. EME is a partnership between the Medical Research Council (MRC) and the NIHR. The EME Programme is accepting stage 1 applications to their commissioned workstream for the following funding opportunities: Mechanisms of action of health interventions Efficacy trials in regenerative medicine Early detection of disease NIHR efficacy and mechanisma evaluation programme - dementia research call Funder: NIHR Closing date: 7 December 2021 This National Institute for Health Research (NIHR) call invites proposals for dementia research to address important health and social care questions. Research could involve any aspect of prevention, diagnosis, treatment, support or care, and related health and social care services. Applications which involve investigators spanning a range of specialties are encouraged and partnership with national charities welcomed. The PHR and HTA programmes are also accepting proposals in this call - see 30 Nov and 5 Jan. More information NIHR NICE rolling call for research studies addressing NICE research recommendations Funder: NIHR Closing date: 7 December 2021 The Efficacy and Mechanism Evaluation Programme is accepting Stage 1 applications for the NICE rolling call for research studies addressing NICE research recommendations. The EME Programme is interested in receiving applications to meet recommendations in research identified in NICE guidance published from 2015 onwards (for the purposes of this call, NICE guidance includes the following: clinical, social care, public health, technology appraisals, interventional procedures and diagnostics). More information NIHR efficacy and mechanism evaluation programme - researcher-led workstream Funder: NIHR Closing date: 7 December 2021 The Efficacy and Mechanism Evaluation (EME) Programme funds ambitious studies evaluating interventions with potential to make a step-change in the promotion of health, treatment of disease and improvement of rehabilitation or long-term care. Within these studies, EME supports research in the mechanisms of diseases and treatments. EME is a partnership between the Medical Research Council (MRC) and the NIHR. The Efficacy and Mechanism Evaluation (EME) Programme is accepting stage 1 applications to their researcher-led workstream. Applications are sought for research into interventions that are based or used by the NHS and its partners. More information NIHR 21/561 James Lind Alliance Priority Setting Partnerships rolling call (EME programme) Funder: NIHR Closing date: 7 December 2021 The Efficacy and Mechanism Evaluation (EME) Programme is accepting stage 1 applications to this funding opportunity. The programme recognises the importance of the research priorities identified by the James Lind Alliance (JLA) Priority Setting Partnerships (PSP) and are interested in receiving high-quality applications which address them. More information Royal College of Surgeons of England - pump priming grants Funder: Royal College of Surgeons Closing date: 7 December 2021 The Royal College of Surgeons of England is offering a limited number of awards of up to £ 10,000 to newly appointed consultants, senior lecturers and post-doctoral trainees (appointed since 2015) in surgery who are working at hospitals and universities within the UK. The aim of the awards is to give assistance to such surgeons in the early stages of their independent research careers. Awards may be used, amongst other things, for small items of equipment, for consumables or for technical assistance. All applicants must be members or fellows of The Royal College of Surgeons of England. Applicants must be consultants, senior lecturers or post-doctoral trainees (appointed since 2015) working in surgery in the UK. More information CRUK: Early Detection and Diagnosis Project Award Funder: CRUK Closing date: 8 December 2021 Early Detection and Diagnosis Project Awards fund science to drive transformational change in how and when early cancers and pre-cancerous states are diagnosed. Early detection and diagnosis (ED&D) research seeks to detect and diagnose consequential precancerous changes and cancer at the earliest possible point at which an intervention might be made, reducing the burden of late-stage disease. ED&D projects will support discovery and translational/clinical research which is mindful of the clinical and population context. More Information NIHR i4i - product development awards, call 23 Funder: NIHR i4i Closing date: 8 December 2021 The NIHR Invention for Innovation (i4i) Programme supports the preclinical and clinical development of medical technologies in areas of existing or emerging patient need. The i4i programme invites proposals to Call 23 of its researcher-led Product Development Awards (PDA). PDAs fund the development of disruptive early-stage medical technologies that address existing or emerging healthcare needs. They support translational projects developing medical devices, in vitro diagnostics and digital health technologies that are patient-focused and for ultimate NHS use. More information Wessex REACH - peer support funding Funder: Wessex REACH Closing date: 10 December 2021 A small amount of funding is available to groups of researchers who wish to create a space for thinking, connecting and problem solving with their peers. Anyone currently working in healthcare, social care or in healthcare-related research in Wessex is eligible. Groups can apply for up to £ 500 to be used over a 1 year period. Send a short summary (up to 500 words) detailing your group, reasons for applying, planned activities, objectives and how they align with building research capacity in Wessex, and budget to info@wessexreach.org.uk . For more detail, contact Beth Stuart . More information THIS Institute environmental sustainability fellowship Funder: The Healthcare Improvement Studies (THIS) Institute Closing date: 15 December 2021 Fellowships to enable individuals to conduct research that will help the NHS increase its capacity to improve environmental sustainability. Focus areas in scope could include energy use, waste disposal, procurement and supply chains, operational processes, transport, hygiene practices, equipment and technology, care processes, device or building design, as well as many other research questions relevant to improving sustainability. Findings should be generalisable or transferable and should contribute to scholarly work as well providing real actions that can be implemented. More information CRUK: Prevention and Population Research Project Awards Funder: CRUK Closing date: 15 December 2021 Prevention and Population Research Awards provide support for focused research proposals centred on key questions in prevention and population research. More Information Closing the Gap collaboration fund Funder: UKRI Closing the Gap Network Closing date: 20 December 2021 Funding to support and encourage new and emerging collaborations in the area of severe mental ill health to develop new research proposals that could be funded through the Closing the Gap Network Plus funds or through other funding bodies. More information Action for A-T - research grants Funder: Action for A-T Closing date: 3 January 2022 Action for A-T funds medical research to speed up the process of identifying a cure for Ataxia Telangiectasia (A-T) or treatments that delay or prevent the disabling effects of this devastating childhood condition. Applications are invited for high quality research projects that have the potential to lead to treatments and cures for Ataxia-Telangiectasia. More information NIHR Health Technology Assessment Programme Researcher-led workstream Funder: NIHR Closing date: 5 January 2022 The Health Technology Assessment Programme is accepting stage 1 applications to their researcher-led evidence synthesis workstream, 21/554. More Information NIHR Health Technology Assessment Programme Researcher-led workstream Funder: NIHR Closing date: 5 January 2022 The Health Technology Assessment Programme is accepting stage 1 applications to their researcher-led workstream, 21/555. More Information NIHR 21/558 NIHR James Lind Alliance Priority Setting Partnerships rolling call (HTA Programme) Funder: NIHR Closing date: 5 January 2022 The Health Technology Assessment (HTA) Programme is accepting stage one applications to this funding opportunity. The programme recognises the importance of the research priorities identified by the James Lind Alliance (JLA) Priority Setting Partnerships (PSP) and are interested in receiving high-quality applications which address them. More Information NIHR 21/559 Dementia research call - Health Technology Assessment (HTA) Programme Funder: NIHR Closing date: 5 January 2022 The Health Technology Assessment (HTA) Programme is accepting stage one applications to this funding opportunity. Dementia is a growing challenge that has become one of the most important health and social care issues facing the world. We need to continue building the evidence base, to improve the lives of people affected by dementia. More Information NIHR Policy Research Programme - evaluation of new funding for inpatient detoxification beds Funder: NIHR Closing date: 6 January 2022 The NIHR funds policy research to enable evidence informed policy making in health and social care. The PRP Programme invites applications for a single research project to qualitatively evaluate an initiative to increase provision of inpatient detoxification to improve drug recovery. It is expected this will be based on in-depth interviews with about 30 inpatients and 30 healthcare professionals with initial contact needed in October-December 2021, a follow-up directly after the detox and a further follow-up after 6 months. The project will complement a quantitative analysis being carried out by Public Health England (PHE). More information NIHR James Lind Alliance Priority Setting Partnerships rolling call (HS&DR programme) Funder: NIHR Closing date: 11 January 2022 The Health Services and Delivery Research (HS&DR) Programme is accepting stage one applications to this funding opportunity. The programme recognises the importance of the research priorities identified by the James Lind Alliance (JLA) Priority Setting Partnerships (PSP) and are interested in receiving high-quality applications which address them and are within the scope of the programme. The JLA Priority Setting Partnerships facilitate patients, carers and clinicians to work collaboratively to identify research priorities in particular areas of health and care. Their aim is to ensure that health research funders are aware of the issues that are important to the people who need to use the research in their daily lives. The NIHR research programmes fund research across the National Health Service (NHS), public health and social care to meet the needs of those who plan, provide and receive care and services. The programmes recognise the importance of the research priorities identified by the James Lind Alliance Priority Setting Partnerships and are interested in receiving high-quality applications which address them. More information NIHR Health Services and Delivery Research Programme (standard researcher-led) Funder: NIHR Closing date: 11 January 2022 The Health Services and Delivery Research (HS&DR) Programme aims to produce rigorous and relevant evidence to improve the quality, accessibility and organisation of health and social care services. The HS&DR Programme is accepting stage 1 applications to their researcher-led workstream. The researcher-led workstream welcomes Stage 1 proposals on topics or research questions identified by researchers within the programme ’ s remit. The aim is to fund research that will lead to improvements in health services that will be of greatest benefit to the NHS and to patients. We are interested in a range of types of research including primary research and evidence synthesis. More information NIHR Invention for Innovation - challenge awards, call 13 Funder: NIHR Closing date: 12 January 2022 The Challenge Awards will fund investigations of MedTech innovations in healthcare settings. The aim is to shorten the evidence gap between the safety/efficacy typical of a newly or nearly CE-marked technology and what is required for decisions by commissioners and regulators. At the same time, this will de-risk the product for follow-on investment. Please note that nearly CE-marked technologies refers to technologies that are currently under Notified Body assessment, whereby all of the mandatory testing has been completed. More information Medical Research Foundation - adolescent dermatology Funder: Medical Research Foundation Closing date: 12 January 2022 The aim of this grant is to increase understanding of the disease mechanisms underpinning skin disorders of relevance to adolescents, and improve diagnosis, treatment and management of these diseases. MRF are inviting applications from clinicians who have the potential to be the research leaders of the future, to support research that will increase understanding of the disease mechanisms underlying adolescent skin disorders. Researchers whose work may lead to better understanding of prevention, treatment or management of these disorders are welcome to apply. More information NIHR Programme Development Grants - competition 32 Funder: NIHR Closing date: 13 January 2022 NIHR Programme Development Grants (PDG) are designed to enable a research team to carry out targeted preparatory work to develop a competitive Programme Grants for Applied Research (PGfAR) funding application. They can also be used to further develop an existing or ongoing PGfAR-funded programme of research. Programme Development Grants are designed to increase the rate and number of successful applications for a full Programme Grant by supporting the completion of the necessary preparatory work to suitably position the research team to submit a competitive Programme Grant application. Applications to PDG are made with the support of an NHS body and other providers of NHS services in England. If an application is successful, a contract will be placed with that organisation for delivery of the research and all funds for the research will be paid to the NHS organisation or other provider of NHS services. more information NIHR Population Health Career Scientist Award Funder: NIHR Closing date: 13 January 2022 The NIHR has launched the Population Health Career Scientist Award (PHCSA), a UK-wide initiative to enable senior researchers to make the next step to Reader/Professor level in their host institutions. The PHCSA forms part of a series of initiatives and investments by NIHR to enable local government to become more research active. This new award will help answer the most important research questions facing decision-makers at local and national levels to improve health and reduce inequalities. There is a desire to attract applicants representing the wide range of disciplines which undertake research in areas which impact the determinants of health (e.g. environmental science, mathematics, architecture, engineering, geography, education, social sciences, social policy, arts). More information NIHR Advanced Fellowship Funder: NIHR Closing date: 13 January 2022 The NIHR Advanced Fellowship funds post-doctoral individuals from a range of health and social care professions who have not yet been awarded a chair. Whether you are someone who has recently been or about to be awarded a PhD, or someone with several years of post-doctoral experience, you could be eligible to apply for an Advanced Fellowship. The Fellowship funds: full salary support, including protected time to concentrate on research research costs a bespoke training and development programme to meet individual needs Applicants who are active clinicians or social workers can request for up to 40% of their time to be dedicated to clinical service/development/practice, which will be covered by the Fellowship. We are particularly welcoming applications from researchers looking to undertake research in: Multiple Long Term Conditions – Multimorbidity (MLTC-M) Dementia More Information Royal Institute for Deaf People - fellowships Funder: RNID Closing date: 13 January 2022 The RNID Fellowship scheme aims to build research capacity in hearing research, by supporting the career development of the UK ’ s most talented new ‘ investigators ’ towards becoming independent scientists. Applications are invited in any of the following areas: Research to underpin the development of treatments for hearing disorders, including tinnitus . Including, but not limited to, medical devices, pharmacological treatments, genetic or cellular therapies – treatments should aim to prevent hearing loss, restore auditory function or silence tinnitus. Research to improve how new treatments for hearing disorders, including tinnitus, are developed and tested . Including research to improve the measurement of auditory function or tinnitus, or to develop models of human hearing disorders, including tinnitus. More information Cancer Research UK drug development project Funder: CRUK Closing date: 14 January 2022 Drug Development Projects are not grant funding awards. The funding is there to develop new cancer treatments from preclinical development through to early phase patient trials. Applicants must have a novel cancer agent needing preclinical and/or clinical development and have supporting in vivo efficacy data. All technology areas are considered, including small molecule, biological and other therapeutics. More information NIHR Doctoral Fellowships - round 7 Funder: NIHR Closing date: 18 January 2022 NIHR Doctoral Fellowships provide funding for individuals to undertake a PhD in an area of NIHR research. As part of the creation of the NIHR Academy, four broad Strategic Themes have been identified which represent key priority areas for the NIHR Academy. Applications received under these Themes will still have to meet the same quality threshold required for funding, but will be given priority if the number of fundable applications exceeds the maximum that can be funded. The Themes are: social care, public health, mental health and health data science. More information Parkinson's UK / Rosetree Trust joint senior research fellowship Funder: Parkinson's UK & Rosetree Trust Closing date: 19 January 2022 Parkinson's UK and Rosetrees Trust are jointly funding the Joint Senior Research Fellowship to support early career researchers with an excellent track record in novel cell culture techniques to establish a highly innovative independent drug discovery programme and become research leaders of the future. With this fellowship scheme, the funders are keen to support the progression of neuroprotective treatments for Parkinson's through the development and use of novel cell culture platforms. More information British Heart Foundation - clinical study grants Funder: British Heart Foundation Closing date: *various* see below For clinical trials and observational studies of specific patient groups, usually costing more than £ 350,000 or lasting more than 3 years. The Clinical Study Grant supports funding for: Interventional clinical trials: trials of specific interventions or pathways of care for the prevention, diagnosis and treatment of cardiovascular disease. Interventions include drugs, surgery, devices, psychological, physical and educational interventions. Observational studies of specific patient groups that are hypothesis led and address a defined clinical question(s) over a fixed timescale (up to 5 years). The population of interest should be a patient population, who will usually be recruited within the NHS. The study should have a predefined outcome(s) that will lead to changes in clinical management directly or will inform the development of a clinical trial to test an intervention. Clinical studies can include a mechanistic evaluation, either as a substudy within a clinical trial or as part of an observational study. Closing dates for proposals: 19 January 2022, 11 May 2022 More information British Heart Foundation - consultant research awards Funder: BHF Closing date: 19 January 2022 This new scheme aims to provide protected time to clinically active consultants to undertake substantial cardiovascular research activities in addition to their clinical roles. They provide up to 2 years full-time equivalent of salary support for the primary applicant, to backfill an equivalent number of NHS PAs. This grant can be taken on a full-time basis or spread across up to 5 years, and additional support costs be also be applied for in each year of an award. There will be two fixed calls for this scheme each year. More information Royal Commission for the Exhibition of 1851 - research fellowships Funder: Royal Commission 1851 Closing date: 19 January 2022 The Royal Commission for the Exhibition of 1851 awards Fellowships for advanced study and research in science, engineering, the built environment and design. 1851 Research Fellowships are intended to give early career scientists or engineers of exceptional promise the opportunity to conduct a research project of their own instigation; an ultimate objective is to contribute to the knowledge base required for a healthy and innovative national culture. Around eight awards are made each year. More information Alzheimer's Research UK - senior research fellowship Funder: Alzheimer's Research UK Closing date: 21 January 2022 Senior Research Fellowships are designed to retain excellent clinical and non-clinical researchers who have a track record of nationally competitive research, and clear plans to manage their own independent research group and become internationally recognised within the field of biomedical dementia research. The purpose of Senior Research Fellowships is to foster both clinical and non-clinical researchers in their “ transition to independence ” . Prospective applicants should a have a strong track record of original and productive research in their area (as evidenced by senior author publication(s) or other equivalent outputs), which shows productivity and impact across past appointments (typically at least one previous post-doctoral appointment). More information Alzheimer's Research UK - major projects Funder: Alzheimer's Research UK Closing date: 21 January 2022 Alzheimer ’ s Research UK is a research charity dedicated to causes, diagnosis, prevention, treatment and cure of Alzheimer ’ s. ARUK work across four key areas of action: Understand the diseases that cause dementia; diagnose people earlier and more accurately; reduce risk, backed by the latest evidence; treat dementia effectively. The Major project grant scheme provides funds for high quality research projects. It is provided to cover salaries (research, technical, students etc), equipment, animal costs and running costs (consumables, travel etc). More information NIHR Health Services & Delivery Research Programme - improving choice, access and uptake of contraception Funder: NIHR Closing date: 21 January 2022 The Health Services and Delivery Research (HS&DR) Programme aims to produce rigorous and relevant evidence to improve the quality, accessibility and organisation of health and social care services. The HS&DR Programme is interested in receiving applications to understand the impact of the pandemic on women ’ s, including transgender and non-binary people ’ s, choices, access and their attitudes and preferences towards contraception, especially towards long-acting reversible contraceptives. It is also important to understand their experiences of initial access to contraception in both general practice and sexual and reproductive health services. We are also interested in research that explores women ’ s, including transgender and non-binary people ’ s, experiences of using these services, and the extent to which their care is fragmented or well-coordinated, and what this indicates in terms of how service provision may need to change to meet future needs. Research into understanding experiences of these services in the context of rapid changes to services from face-to-face to remote during the COVID-19 pandemic is also of interest. More information Paget's Association - research grants Funder: Paget's Association Closing date: 25 January 2022 The Paget's Association is a national UK charity providing information and support to all those affected by Paget ’ s Disease of Bone. The Association funds quality research, raises awareness and supports professionals to achieve excellence in care and research. The Paget ’ s Association invites applications for Research Project Grants in all areas of Paget ’ s Disease of Bone. Collaborative research is strongly encouraged, including through our Paget ’ s Association Centres of Excellence (PACEs). More information UHS R&D small grants scheme 2021 Funder: University Hospital Southampton R&D Closing date: 26 January 2022 Grant applications are invited from investigators across the Southampton Partnership for research funding proposals that align with research portfolios within UHS clinical divisions, and/or the UHS/UoS research infrastructure. Up to £ 50k is available for projects up to three years in duration. The application form is available here . Southampton Hospitals Charity - research funding scheme Funder: Southampton Hospitals Charity Closing date: 26 January 2022 Southampton Hospitals Charity (SHC) has partnered with the Research & Development team to fund innovative research projects with the potential to demonstrate direct benefit to UHS patients. The total number of projects awarded will be determined by quality and impact. An exceptionally strong case for funding should be presented for any project costing over £ 50k. Fundraising will launch once the successful projects have been selected and projects are therefore not expected to commence until 9-12 months after award confirmation i.e., not before January 2023. All research designs, disciplines, and scope, except for basic science projects, will be considered. SHC has identified a number of research areas for this round, based on the potential for timely fundraising: cancer care cardiology child health, including neonatal neurology ophthalmology The application form is available here More information NIHR i4i - dementia: digital approaches for early detection, diagnosis and stratification Funder: NIHR Closing date: 26 January 2022 The NIHR Invention for Innovation (i4i) Programme is inviting applications for a Dementia specific funding stream aimed at the research and development of digital approaches for the early detection, diagnosis and stratification of individuals with dementia. The i4i Programme supports the research and development of innovative medical technologies that have demonstrated proof-of-concept and have a clear developmental pathway towards new products for ultimate NHS use. More information MRC Neurosciences and Mental Health - funding opportunity Funder: MRC Closing date: 26 January 2022 Apply for funding for research projects focused on neurosciences and mental health. The MRC Neurosciences and Mental Health Board funds research in neurosciences, mental health and disorders of the human nervous system. The aim is to transform understanding of the physiology and behaviour of the human nervous system throughout the life course in health and in illness, as well as how to treat and prevent disorders of the brain. The research supported by UKRI includes the interactions between the nervous system and other parts of the body, the brain, mental health and physical health. They are also interested in how episodes throughout life impact on lifelong mental and neurological health. More information Leukaemia UK - John Goldman Fellowships Funder: Leukaemia UK Closing date: 31 January 2022 Leukaemia UK John Goldman Fellowships are aimed at early career researchers with a passion for science, a desire to develop new ideas and translate scientific advances into clinical practice. Successful applicants will demonstrate that they are the potential scientific/clinical leaders of the future. Their proposed research project must be novel with the capacity to make advances in our knowledge of leukaemia and related diseases and the development of new and kinder treatments. Applications are accepted from scientists and clinician-scientists working in UK universities, research institutions or hospitals. More information Pancreatic Cancer UK - joint funded clinical research fellowship Funder: Pancreatic Cancer UK & Association of Surgeons of GB and Ireland Closing date: 31 January 2022 The Association of Surgeons of Great Britain and Ireland (ASGBI) and Pancreatic Cancer UK Fellowship: Supports a Trainee or Junior Consultant (within 5 years of first appointment) with an interest in advancing the clinical management of pancreatic cancer. This individual will visit centres of excellence abroad and bring this experience back to the NHS to advance our clinical expertise within the UK. More information British Scoliosis Research Foundation - research grants Funder: BSRF Closing date: 31 January 2022 The British Scoliosis Research Foundation (BSRF) promotes research into the treatment of scoliosis in the UK. Each year the BSRF funds a great deal of research into scoliosis and periodically holds an international symposium to spread the knowledge gained from research. BSRF Research Grants are open to appropriately qualified professionals such as scientists, clinicians, and allied health professionals (nurses, psychologists or physiotherapists). All applications will be considered, however, applicants are advised to submit their proposal under one of the following three headings: Small exploratory grant New investigation grant Major research grant More information British Infection Association - project grants Funder: British Infection Association Closing date: 31 January 2022 The BIA aims to foster excellence in all aspects of clinical infection-related research by supporting patient-facing researchers-in-training to achieve high-quality clinical and basic research in the field of infection. BIA Project Grants provide consumables costs for trainees undertaking an infection-related research project in an academic centre in the UK or Ireland. It is envisaged funds would be used to support preliminary study in a field with intention of developing the work either through a research fellowship or as an independent investigator. More information The Urology Foundation - innovation and research grant Funder: The Urology Foundation Closing date: 31 January 2022 The Urology Foundation (TUF) is dedicated to beating all urology diseases through cutting-edge research and leading education and training to ensure that fewer lives will be devastated. The Urology Foundation (TUF) will fund projects up to a value of £ 60,000 that seek to use new, exciting, innovative approaches to address urological diseases and disorders. The projects must either (a) aim to create innovative treatments or devices, (b) aim to deliver innovative care pathways or (c) aim to use innovative research techniques or methods. Please note that innovation is necessary but not sufficient for a successful application. For example, a project with innovative methodology would need to lead to a practical end point and similarly, a project aiming to design an innovative treatment would need to have a practical methodology. More information Daphne Jackson Trust and the Kennedy Trust for Rheumatology Research - rheumatology fellowship Funder: Daphne Jackson Trust & Kennedy Trust for Rheumatology Research Closing date: 31 January 2022 Applications are invited for a Kennedy Trust sponsored three year Daphne Jackson Fellowship to be held at any UK university or research establishment. The Fellowship is intended for a scientist wishing to return to research into any clinical or pre-clinical subject in the field of rheumatology and related musculoskeletal or immunological diseases More information Diabetes UK Harry Keen intermediate clinical fellowship Funder: Diabetes UK Closing date: January 2022 The Diabetes UK Harry Keen Intermediate Clinical Fellowship allows outstanding medically qualified professionals and other clinically qualified professionals – including nurses, pharmacists and members of the Allied Health Professions, who have gained a PhD or equivalent (e.g. MD (Res)) – to establish themselves as independent researchers with a view to a long-term career as a clinical research leader in the field of diabetes. It is expected that the app
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BRC Assistant Project Manager_ Study Manager PS_15 11 2023

Description: EMPLOYMENT CRITERIA / PERSON SPECIFICATION The purpose of this specification is to identify the attributes required by applicants to perform the duties in the job description. The specification will be used to shortlist applicants and to compare how well candidates match the agreed specification. It will also be used by potential candidates to understand expectations and identify how their skills, behaviours and experience will be assessed. Post Title Assistant Clinical Research Project Manager / Study Manager Directorate/Department Southampton NIHR Biomedical Research Centre Assessment Method Key (Note for candidates: This is not an exhaustive list and if you have any questions about the assessment methods listed, please contact the team member named on the job advert.) Interview These criteria will be assessed during an interview, should you be shortlisted. Application These criteria will be assessed at shortlisting; therefore anything not advised in your application can not be scored. Presentation During an interview you may be asked to produce a presentation, this is when these criteria will be assessed. Physical requirements of the post Requirements Health and physical abilities sufficient for the post (if necessary with reasonable adjustments with respect to the Equality Act/Disability Discrimination Act). Assessment Method Application Qualifications / training required Requirements Educated to degree level or equivalent Specialist qualification or significant experience In Project Management Evidence of on-going professional development International Conference on Harmonisation/Good Clinical Practice (ICH/GCP) training Previous or relevant experience necessary Assessment Method Application Application and Interview Application and Interview Application Essential X Desirable Essential x x x x Desirable EMPLOYMENT CRITERIA / PERSON SPECIFICATION The purpose of this specification is to identify the attributes required by applicants to perform the duties in the job description. The specification will be used to shortlist applicants and to compare how well candidates match the agreed specification. It will also be used by potential candidates to understand expectations and identify how their skills, behaviours and experience will be assessed. Requirements Experience in research management Research background Advanced understanding of Microsoft applications for managing and analysing information, e.g. Word and Excel Awareness of current legislation regarding research governance issues Significant experience in conducting or organising clinical research trials within NHS setting Recent experience in project management of large/complex studies Knowledge of UK Framework for Health and Social Care Research Recent NHS experience Experience of managing a study portfolio within a large organisation Experience or a detailed knowledge of the UK trial regulatory submission process Aptitudes and skills required Requirements Motivation for research Exceptional attention to detail Good organisational skills Able to work alone or as part of a team Able to prioritise tasks and cope with deadlines Proactive attitude Clear and polite verbal communication Ability to work under own initiative and independently outside the department without direct supervision. Mature and sound judgement, with ability to solve problems Assessment Method Application and Interview Application and Interview Application Application and Interview Application and Interview Application and Interview Application and Interview Application Application and Interview Application and Interview Assessment Method Application and Interview Application and Interview Application and Interview Application and Interview Application and Interview Application and Interview Application and Interview Application and Interview Application and Interview Essential x x x Desirable x x x x x x x Essential x x x x x x x x x Desirable EMPLOYMENT CRITERIA / PERSON SPECIFICATION The purpose of this specification is to identify the attributes required by applicants to perform the duties in the job description. The specification will be used to shortlist applicants and to compare how well candidates match the agreed specification. It will also be used by potential candidates to understand expectations and identify how their skills, behaviours and experience will be assessed. Special requirements of the post Requirements Ability to attend training courses and meetings on and off site Assessment Method Interview Essential x Desirable Values and behaviours Requirements Able to demonstrate behaviours that meet the Trust Values • Patients First • Always Improving • Working Together Assessment Method Application and Interview Essential Desirable X
Url: /Media/Southampton-Clinical-Research/Downloads/BRC-Assistant-Project-Manager-Study-Manager-PS-15-11-2023.pdf

Free Training: Pre-doctoral Clinical Academic Fellowship (PCAF) Scheme Workshop

Description: Auto Generated Title Free training for nurses, midwives and allied health professionals. Have you ever wanted
Url: /ClinicalResearchinSouthampton/For-researchers/Education-and-training/Events/Free-Training-Pre-doctoral-Clinical-Academic-Fellowship-PCAF-Scheme-Workshop.aspx

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BRC Assistant Project Manager_ Study Manager PS_15 11 2023

Free Training: Pre-doctoral Clinical Academic Fellowship (PCAF) Scheme Workshop

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