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Stroke research

Southampton is a National Institute of Health (NIHR) Hyperacute Stroke Research Centre. This means that we aim to recruit many patients in the very early stages of having had a stroke in order to minimise brain damage. This may be through medications, surgery to remove blood clots, or other treatments.

You may be approached by a member of your clinical care team or the stroke research team during or after your hospital admission, asking if you want to take part in our research. They will provide you with information about what’s involved; there is no obligation to take part, and your care will not be affected if you decline.

In addition, we have a broad portfolio of randomised clinical trials and other high quality clinical studies. These cover:

  • prevention
  • acute care
  • primary care
  • rehabilitation
  • service development
  • translational research.

Studies currently recruiting

Clinical studies we are currently recruiting in to include:

  • Antiplatelet Secondary Prevention International Randomised study after INtracerebral haemorrhaGe (ASPIRING)
  • Intracranial stenting in case of treatment failure for LVO stroke (ICARUS)
  • LACunar Intervention Trial-3: Assessment of safety and efficacy of cilostazol and isosorbide mononitrate to prevent recurrent lacunar stroke and progression of cerebral small vessel disease (LACI-3)
  • Metoclopramide for Avoiding Pneumonia after Stroke (MAPS-2)
  • Remote Ischaemic Conditioning After Stroke 3: A multicentre randomised controlled trial (RECAST-3)
  • Safety and efficacy study of Sovateltide in patients with acute cerebral ischaemic stroke (Respect-ETB)
  • Tranexamic acid for Hyperacute Spontaneous Intracerebral Haemorrhage (TICH-3)

Stroke clinical trials information

For further information about our studies, please contact the neurosurgery and stroke research team on: