Breast cancer clinical trials
EndoNET
https://www.isrctn.com?ISRCTN11896599
EndoNET is a Phase III, randomised trial evaluating whether a period of endocrine therapy prior to surgery (neoadjuvant endocrine therapy) reduces surgical burden resulting in better health-related quality of life (QoL) for post-menopausal women with ER+, HER2- invasive breast cancer who do not require chemotherapy.
SMALL
The study is a Phase III, randomised, multi-centre trial. The study will help experts learn whether some women with small breast cancers, which are at low risk of spreading, can be safely treated by removal of the cancer using a biopsy needle (under a local anaesthetic) instead of an operation. Some women may be able to avoid unnecessary breast surgery in the future as a direct result of the knowledge gained from you taking part in this study.