One year on: New machine at UHS transforming care for sickle cell patients

The number of sickle cell patients receiving red cell exchange transfusions at University Hospital Southampton (UHS) has increased by 25% since the introduction of a new machine last year.

The Spectra Optia® Apheresis System enhances treatment options, and can significantly improve quality of life for those living with sickle cell disease.

Sickle cell disease is a serious inherited blood disorder that affects the shape and function of red blood cells. It is particularly common in people of African or Caribbean descent, and can cause severe pain, complications, and frequent hospitalisations.

Red cell exchange transfusions are a crucial treatment option, replacing sickled cells with healthy red blood cells to prevent complications and reduce painful episodes, known as crises.

Abena Ntiri-Akuffo, a UHS patient who receives regular exchange transfusions using the new machine, has experienced life-changing benefits. She said: “I want to say thank you to everyone who donates blood. For me, it’s a massive lifesaver to be able to come here (UHS) every month to get a blood transfusion and red cell exchange. It ensures I can be in the best health possible, and I’m really grateful for it.”

31-year-old Abena has seen a dramatic reduction in the number of painful sickle cell crises she experiences - which previously led to frequent hospital admissions. “I’ve been having exchange transfusions since 2020, going from 13 or 14 hospital stays per year down to maybe one a year, and none this past 12 months. It’s really changed my life, and has allowed me to work full-time, travel, and enjoy my life to the full.”

The new machine, funded by NHS England, automates the red cell exchange process, making the treatment faster, more efficient, and reducing the need for additional top-up transfusions. This has led to improved pain management and a lower risk of crisis episodes.

Carole Momber, haemoglobinopathies nurse specialist on C7 ward at UHS, said: “Over the past year, the introduction of this machine has had a huge impact on the care we can provide to our sickle cell patients. By increasing access to red cell exchange we have been able to reduce hospital admissions, improve patient outcomes, and ultimately enhance quality of life. It is fantastic to see the difference this technology is making.”

UHS was one of 22 NHS Trusts selected to receive the new equipment as part of a £1.5 million national investment to improve care for people living with sickle cell disease across the country.

The hospital continues to encourage blood donation, particularly from Black and mixed-heritage donors, to help ensure the best possible treatment for sickle cell patients. More information on how to donate can be found at www.blood.co.uk.