Slaght, Dr Seán J.

BSc (Hons), PhD, MB, BCh, FRCP (London)Slaght, Dr Sean (neurology) photo





Training and education

  • BSc (Hons) - Cardiff University, 1999
  • PhD - Cardiff University, 2002
  • MB BCh (bachelor of medicine, bachelor of surgery) - University of Wales, 2004
  • Junior doctor training - Cardiff and London - 2004 to 2008
  • Specialist neurology training - Southampton, 2008 to 2012
  • Fellowship in complex epilepsy - King's College Hospital, London, 2012 to 2013


Dr Slaght joined the Trust as a consultant neurologist in 2014. He also worked here between 2008 and 2012 as a registrar.

As well as providing general neurology and specialist epilepsy services to outpatients in Portsmouth, Dr Slaght runs a specialist epilepsy clinic here at Southampton General Hospital. He is also the governance lead for neuroscience.

Dr Slaght is interested in all areas of general and acute neurology (neurological conditions that require urgent care). His subspecialty interest is complex epilepsy, including the preparation for epilepsy surgery.


For his PhD, Dr Slaght studied the cellular mechanism of absence seizures (seizures in the form of a sudden loss of awareness). He is the principal investigator for many clinical trials studying epilepsy and non-epileptic attack disorder, a non-epilepsy related condition that causes patients to have seizures.

Dr Slaght has published the following articles:

  • Slaght SJ, Nashef L. An audit of external trigeminal nerve stimulation (eTNS) in epilepsy. Seizure. 2017 Nov;52:60-62.
  • Slaght SJ, Weir NU, Lovett JK. The workload of stroke thrombolysis: a prospective study in a district general hospital setting. Acute Med. 2011;10(1):10-2.
  • Mahon S, Vautrelle N, Pezard L, Slaght SJ, Deniau JM, Chouvet G, Charpier S. Distinct patterns of striatal medium spiny neuron activity during the natural sleep-wake cycle. J Neurosci. 2006 Nov 29;26(48):12587-95.  
  • Slaght SJ, Paz T, Chavez M, Deniau JM, Mahon S, Charpier S. On the activity of the corticostriatal networks during spike-and-wave discharges in a genetic model of absence epilepsy. J Neurosci. 2004 Jul 28;24(30):6816-25.
  • Slaght SJ, Paz T, Mahon S, Maurice N, Charpier S, Deniau JM. Functional organization of the circuits connecting the cerebral cortex and the basal ganglia: implications for the role of the basal ganglia in epilepsy. Epileptic Disord. 2002 Dec;4 Suppl 3:S9-22.  
  • Slaght SJ, Leresche N, Deniau JM, Crunelli V, Charpier S. Activity of thalamic reticular neurons during spontaneous genetically determined spike and wave discharges. J Neurosci. 2002 Mar 15;22(6):2323-34.


If you're a patient in Southampton, you can contact Dr Slaght via his secretary Mary Hayes - call 023 8120 5771 or send an email.

Portsmouth patients can contact his secretaries Josie Steele or Caroline Stock at Queen Alexandra Hospital on 023 9228 6000 (ext. 6807) or email or