Ashton-Key, Dr Margaret

Dr Margaret Ashton-KeyDM FRCPath


Histopathology and cytology


Haematopathology, gynaecological pathology and gynaecological cytology

Training and education

  • University of Southampton medical school
  • Senior house officer, histopathology, Southampton
  • Registrar, histopathology, John Radcliffe Hospital, Oxford
  • Graham Scholar (research fellow), University College London
  • Clinical lecturer, honorary senior registrar, University College London 


Dr Ashton-Key has worked for the Trust since November 2003. 

A consultant histopathologist since 1996, Dr Ashton-Key worked at Brighton and Sussex University Hospitals before moving to Southampton in 2002. She was inspired by haematopathology whilst working as an senior house officer with Professor Dennis Wright, and further developed her expertise at Oxford and UCL. Dr Ashton-Key's DM thesis investigated the value of new techniques in lymphoma diagnosis.

Key achievements

Nationally and internationally recognised haematopathologist. 

Awards and prizes

  • Clinical prize in ophthalmology, 1988
  • Leighton's ophthalmology prize, 1988
  • Final BM, Distinction in Clinical Medicine, 1989
  • Pathological Society meeting slide seminar prize, 1996
  • Author of a chapter in ‘Diagnostic Cytopathology’, awarded first prize in the BMA Medical Book Competition, 2003
  • Winner British Association of Gynaecological Pathology quiz, 2007.


Dr Ashton-Key is interested in clinically orientated research, with a particular empahsis on immunohistochemistry and lymphomas.

  • Conner J, Ashton-Key M. Clinical and Immunohistochemical study of Primary Diffuse Large B-Cell Lymphomas of the Gastrointestinal Tract. Histopathology 2007; 51: 697 – 703
  • Ashton-Key M, Diss TC, Du M, Isaacson PG. Molecular analysis of T cell clonality in ulcerative jejunitis and Enteropathy Associated T cell lymphoma. Am J Pathol 1997;151:493-498.
  • Ashton-Key M, Diss TC, Isaacson PG, Smith MEF. A comparative study of the value of immunohistochemistry and the polymerase chain reaction in the diagnosis of follicular lymphoma. Histopathology 1995;27:501-508.