Crabb, Dr Simon

Simon CrabbBSc, MBBS, MRCP, PhD


Medical oncology


Genitourinary cancers (bladder, prostate and kidney cancers)

Training and education

Dr Crabb read medicine at St George's Hospital medical school, London. After junior doctor posts at various London teaching hospitals he trained in the care of patients with cancer in Southampton. He undertook his doctoral research as a Cancer Research UK clinical research fellow at the University of Southampton and completed a clinical research fellowship at the British Columbia Cancer Agency in Vancouver before returning to Southampton.


Dr Crabb has worked for the Trust since 2009 as an associate professor and honorary consultant in medical oncology. He specialises in the care of patients with cancers of the genitourinary tract including bladder, prostate and kidney cancers. He also plays a lead role in the delivery of phase I cancer clinical trials at Southampton.

Key achievements

  • An active translational and clinical research program to develop new treatments for genitourinary cancers including a busy clinical trials portfolio (described in detail on the University of Southampton website)
  • Chief or national lead investigator for multiple clinical trials for prostate and bladder cancer including the ProCAID, SPIRE, BL-13 and GUSTO trials
  • Member of the National Cancer Research Initiative groups for bladder and renal cancers and prostate cancer – and past chair of the advanced bladder cancer subgroup
  • Member of the Cancer Research UK experimental medicine expert review panel
  • Chair of the Genomics England Clinical Interpretation Partnership for bladder cancer for the 100,000 Genomes Project
  • Lead for phase I cancer clinical trials at University Hospital Southampton

Awards and prizes

  • Pollock Prize
  • Novartis Canadian Young Investigator Award, 2007


Dr Crabb's research interests include the development of new therapeutic options for genitourinary cancers.

Find out about Dr Crabb's publications.