Crabb, Dr Simon

Dr Simon CrabbBSc, MBBS, MRCP, PhD


Medical oncology


Genitourinary cancers (bladder, prostate and kidney cancers)

Training and education

Dr Crabb read medicine at St George's Hospital medical school, London. After junior doctor posts at various London teaching hospitals he trained in the care of patients with cancer in Southampton. He undertook his doctoral research as a Cancer Research UK clinical research fellow at the University of Southampton and completed a clinical research fellowship at the British Columbia Cancer Agency in Vancouver before returning to Southampton.


Dr Crabb has worked for the Trust since 2009 as an associate professor and honorary consultant in medical oncology. He specialises in the care of patients with cancers of the genitourinary tract including bladder, prostate and kidney cancers. He also plays a lead role in the delivery of phase I cancer clinical trials at Southampton.

Key achievements

  • An active basic and clinical research program to develop new treatments for genitourinary cancers including a busy clinical trials portfolio (described in detail on the University of Southampton website
  • Chief investigator for the ProCAID and POLERISE clinical trials in prostate cancer and the SPIRE clinical trial in bladder cancer
  • Member of the National Cancer Research Initiative clinical studies groups for bladder and renal cancers and prostate cancer - also chair of the advanced bladder cancer subgroup
  • Member of the Cancer Research UK experimental medicine expert review panel
  • Past member of the executive committee for the British Association for Cancer Research
  • Lead for the phase I cancer clinical trials clinic at University Hospital Southampton

Awards and prizes

  • Pollock Prize
  • Novartis Canadian Young Investigator Award, 2007


Dr Crabb's research interests include the development of new therapeutic options for genitourinary cancers.

Find out about Dr Crabb's publications.